Effect of refractive status and axial length on peripapillary retinal nerve fibre layer thickness: An analysis using 3D OCT

V. Sowmya, V. R. Venkataramanan, K. P. Vishnu Prasad

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Accurate measurement of retinal nerve fiber layer (RNFL) is now possible with the high resolution optical coherence tomography (OCT). Effect of refractive status of the eye on RNFL thickness may be relevant in the diagnosis of glaucoma and other optic nerve diseases. Aim: To assess the RNFL thickness and compare its correlation with refractive status and axial length of the eye. Material and Methods: Three hundred eyes of 150 patients were included in this study, who underwent RNFL analysis using TOPCON 3D OCT 2000. Analysis of variance has been used to find the significance of study parameters between the study groups. Results: The study showed that refractive status/axial length affected the peripapillary RNFL thickness significantly. Conclusion: The study suggests that the diagnostic accuracy of OCT may be improved by considering refractive status and axial length of the eye when RNFL is measured.

Original languageEnglish
JournalJournal of Clinical and Diagnostic Research
Volume9
Issue number9
DOIs
Publication statusPublished - 01-09-2015
Externally publishedYes

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Optical tomography
Optical Coherence Tomography
Nerve Fibers
Fibers
Eye Axial Length
Optic Nerve Diseases
Analysis of variance (ANOVA)
Glaucoma
Optics
Analysis of Variance

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

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abstract = "Background: Accurate measurement of retinal nerve fiber layer (RNFL) is now possible with the high resolution optical coherence tomography (OCT). Effect of refractive status of the eye on RNFL thickness may be relevant in the diagnosis of glaucoma and other optic nerve diseases. Aim: To assess the RNFL thickness and compare its correlation with refractive status and axial length of the eye. Material and Methods: Three hundred eyes of 150 patients were included in this study, who underwent RNFL analysis using TOPCON 3D OCT 2000. Analysis of variance has been used to find the significance of study parameters between the study groups. Results: The study showed that refractive status/axial length affected the peripapillary RNFL thickness significantly. Conclusion: The study suggests that the diagnostic accuracy of OCT may be improved by considering refractive status and axial length of the eye when RNFL is measured.",
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Effect of refractive status and axial length on peripapillary retinal nerve fibre layer thickness : An analysis using 3D OCT. / Sowmya, V.; Venkataramanan, V. R.; Vishnu Prasad, K. P.

In: Journal of Clinical and Diagnostic Research, Vol. 9, No. 9, 01.09.2015.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of refractive status and axial length on peripapillary retinal nerve fibre layer thickness

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AU - Sowmya, V.

AU - Venkataramanan, V. R.

AU - Vishnu Prasad, K. P.

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AB - Background: Accurate measurement of retinal nerve fiber layer (RNFL) is now possible with the high resolution optical coherence tomography (OCT). Effect of refractive status of the eye on RNFL thickness may be relevant in the diagnosis of glaucoma and other optic nerve diseases. Aim: To assess the RNFL thickness and compare its correlation with refractive status and axial length of the eye. Material and Methods: Three hundred eyes of 150 patients were included in this study, who underwent RNFL analysis using TOPCON 3D OCT 2000. Analysis of variance has been used to find the significance of study parameters between the study groups. Results: The study showed that refractive status/axial length affected the peripapillary RNFL thickness significantly. Conclusion: The study suggests that the diagnostic accuracy of OCT may be improved by considering refractive status and axial length of the eye when RNFL is measured.

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