Abstract
Dose matched comparison between copper complex of tolmetin (Tol-Cu) and tolmetin (Tol) was carried out in male albino rats bearing either sutured incision, dead space or excision wounds. Results showed that Tol significantly decreased tensile strength of incision and dead space wound. This effect was totally reversed by copper present in Tol-Cu. Tol-Cu shared the significant suppressant effect of Tol on granulation formation and its collagen content. Tol suppressed wound contraction and epithelialization and copper complex of Tol antagonised the suppressant effect of Tol on wound contraction and epithelialization.
| Original language | English |
|---|---|
| Pages (from-to) | 201-204 |
| Number of pages | 4 |
| Journal | Indian Journal of Experimental Biology |
| Volume | 33 |
| Issue number | 3 |
| Publication status | Published - 01-01-1995 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Bioengineering
Cite this
Somayaji, S. N., Jacob, A. P., & Bairy, K. L. (1995). Effect of tolmetin and its copper complex on wound healing. Indian Journal of Experimental Biology, 33(3), 201-204.