Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count

An experiment on cadmium exposed rats

N. A. Vinodini, Pratik Kumar Chatterjee, Kunal, V. B. Suman, K. S. Rashmi, A. K. Nayanatara, N. Anupama, Ramesh M. Bhat, P. Sheela Joice

Research output: Contribution to journalArticle

Abstract

Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

Original languageEnglish
Pages (from-to)689-693
Number of pages5
JournalPharmacognosy Journal
Volume11
Issue number4
DOIs
Publication statusPublished - 01-01-2019

Fingerprint

Moringa
Poisons
Moringa oleifera
Cadmium
Platelet Count
Control Groups
Wistar Rats
Animal Models

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

Cite this

Vinodini, N. A. ; Chatterjee, Pratik Kumar ; Kunal ; Suman, V. B. ; Rashmi, K. S. ; Nayanatara, A. K. ; Anupama, N. ; Bhat, Ramesh M. ; Sheela Joice, P. / Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count : An experiment on cadmium exposed rats. In: Pharmacognosy Journal. 2019 ; Vol. 11, No. 4. pp. 689-693.
@article{cbc07979dddc49e58a68403fd48542a5,
title = "Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats",
abstract = "Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.",
author = "Vinodini, {N. A.} and Chatterjee, {Pratik Kumar} and Kunal and Suman, {V. B.} and Rashmi, {K. S.} and Nayanatara, {A. K.} and N. Anupama and Bhat, {Ramesh M.} and {Sheela Joice}, P.",
year = "2019",
month = "1",
day = "1",
doi = "10.5530/pj.2019.11.109",
language = "English",
volume = "11",
pages = "689--693",
journal = "Pharmacognosy Journal",
issn = "0975-3575",
publisher = "Pharmacognosy Network Worldwide",
number = "4",

}

Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count : An experiment on cadmium exposed rats. / Vinodini, N. A.; Chatterjee, Pratik Kumar; Kunal; Suman, V. B.; Rashmi, K. S.; Nayanatara, A. K.; Anupama, N.; Bhat, Ramesh M.; Sheela Joice, P.

In: Pharmacognosy Journal, Vol. 11, No. 4, 01.01.2019, p. 689-693.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count

T2 - An experiment on cadmium exposed rats

AU - Vinodini, N. A.

AU - Chatterjee, Pratik Kumar

AU - Kunal,

AU - Suman, V. B.

AU - Rashmi, K. S.

AU - Nayanatara, A. K.

AU - Anupama, N.

AU - Bhat, Ramesh M.

AU - Sheela Joice, P.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

AB - Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

UR - http://www.scopus.com/inward/record.url?scp=85071227719&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071227719&partnerID=8YFLogxK

U2 - 10.5530/pj.2019.11.109

DO - 10.5530/pj.2019.11.109

M3 - Article

VL - 11

SP - 689

EP - 693

JO - Pharmacognosy Journal

JF - Pharmacognosy Journal

SN - 0975-3575

IS - 4

ER -