Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats

N. A. Vinodini, Pratik Kumar Chatterjee, Kunal, V. B. Suman, K. S. Rashmi, A. K. Nayanatara, N. Anupama, Ramesh M. Bhat, P. Sheela Joice

Research output: Contribution to journalArticle

Abstract

Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

Original languageEnglish
Pages (from-to)689-693
Number of pages5
JournalPharmacognosy Journal
Volume11
Issue number4
DOIs
Publication statusPublished - 01-01-2019

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

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