Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns

I. Karuna Sagar, C. N. Nagesha, P. Gundu Rao

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Abstract

The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
JournalBurns
Volume6
Issue number2
DOIs
Publication statusPublished - 01-01-1979
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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