Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns

I. Karuna Sagar, C. N. Nagesha, P. Gundu Rao

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The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
Issue number2
Publication statusPublished - 01-01-1979
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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