Effects of metformin use in pregnant patients with polycystic ovary syndrome

Kashif Khan, Pratap Kumar

Research output: Contribution to journalReview articlepeer-review

14 Citations (Scopus)

Abstract

Use of metformin throughout pregnancy in women with polycystic ovary syndrome (PCOS) has shown to reduce the rates of early pregnancy loss, preterm labor, and prevention of fetal growth restriction. Metformin has been shown to have encouraging effects on several metabolic aspects of polycystic ovarian syndrome, such as insulin sensitivity, plasma glucose concentration and lipid profile and since women with PCOS are more likely than healthy women to suffer from pregnancy-related problems like early pregnancy loss, gestational diabetes mellitus and hypertensive states in pregnancy, the use of metformin therapy in these patients throughout pregnancy may have beneficial effects on early pregnancy loss and development of gestational diabetes.

Original languageEnglish
Pages (from-to)166-169
Number of pages4
JournalJournal of Human Reproductive Sciences
Volume5
Issue number2
DOIs
Publication statusPublished - 01-05-2012

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine

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