Efficacy of erbium YAG laser-assisted autologous epidermal grafting in vitiligo

G. S. Pai, V. Vinod, A. Joshi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background. Of the various modalities of therapy available for the treatment of vitiligo, a combination of psoralen + ultraviolet A (PUVA) with autologous epidermal grafting appears to offer the best results. The erbium YAG laser can be used to prepare the recipient site in both punch grafting and suction blister grafting. Methods. In this study 29 subjects, 26 with localized and three with generalized stable vitiligo, had received pregrafting PUVA and underwent further PUVA starting 2 weeks after surgery until maximal pigmentation was achieved. The erbium YAG laser was used on 16 subjects; the recipient site for punch grafting was prepared with laser and minigrafts harvested by manual punch were placed into the prepared sites. For suction blister grafting, the site was dermabraded with a laser and the harvested blister roof (created using suction apparatus) was transplanted on to the site. Results. More than two-thirds (68.75%) of the subjects who were punch grafted using a laser showed repigmentation of more than 75%, but only one-half of those who underwent conventional punch grafting showed a similar response. All subjects with laser-assisted suction blister grafting showed a good response, compared with only 60% of thoge who underwent conventional suction blister grafting. Conclusions. The results obtained with laser-assisted grafting are more satisfactory than those achieved with conventional grafting techniques. We found that the repigmentation zones are larger (up to 9 mm in the former vs. 3 mm in the latter) and cobblestoning does not occur with laser-assisted grafting. Also, the procedure is precise, relatively atraumatic and can be performed rapidly even when covering vast areas.

Original languageEnglish
Pages (from-to)604-606
Number of pages3
JournalJournal of the European Academy of Dermatology and Venereology
Volume16
Issue number6
DOIs
Publication statusPublished - 01-01-2002
Externally publishedYes

Fingerprint

Vitiligo
Solid-State Lasers
Suction
Blister
Lasers
Ficusin
Pigmentation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

Cite this

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title = "Efficacy of erbium YAG laser-assisted autologous epidermal grafting in vitiligo",
abstract = "Background. Of the various modalities of therapy available for the treatment of vitiligo, a combination of psoralen + ultraviolet A (PUVA) with autologous epidermal grafting appears to offer the best results. The erbium YAG laser can be used to prepare the recipient site in both punch grafting and suction blister grafting. Methods. In this study 29 subjects, 26 with localized and three with generalized stable vitiligo, had received pregrafting PUVA and underwent further PUVA starting 2 weeks after surgery until maximal pigmentation was achieved. The erbium YAG laser was used on 16 subjects; the recipient site for punch grafting was prepared with laser and minigrafts harvested by manual punch were placed into the prepared sites. For suction blister grafting, the site was dermabraded with a laser and the harvested blister roof (created using suction apparatus) was transplanted on to the site. Results. More than two-thirds (68.75{\%}) of the subjects who were punch grafted using a laser showed repigmentation of more than 75{\%}, but only one-half of those who underwent conventional punch grafting showed a similar response. All subjects with laser-assisted suction blister grafting showed a good response, compared with only 60{\%} of thoge who underwent conventional suction blister grafting. Conclusions. The results obtained with laser-assisted grafting are more satisfactory than those achieved with conventional grafting techniques. We found that the repigmentation zones are larger (up to 9 mm in the former vs. 3 mm in the latter) and cobblestoning does not occur with laser-assisted grafting. Also, the procedure is precise, relatively atraumatic and can be performed rapidly even when covering vast areas.",
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Efficacy of erbium YAG laser-assisted autologous epidermal grafting in vitiligo. / Pai, G. S.; Vinod, V.; Joshi, A.

In: Journal of the European Academy of Dermatology and Venereology, Vol. 16, No. 6, 01.01.2002, p. 604-606.

Research output: Contribution to journalArticle

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AU - Joshi, A.

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