Electronic structures and spectra of 6-mercaptopurine and 6-thioguanine

C. Santhosh, P. C. Mishra

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Ultraviolet absorption, steady-state fluorescence and excitation spectra of 6-mercaptopurine (6MP) and 6-(thioguanine) (6TG) have been studied, and excited state life-time measurements on their fluorescence performed. The experimental results have been interpreted with the help of molecular orbital calculations. The study shows that these molecules predominantly exist in thione forms. The properties of the molecules have been compared with those of guanine and the possible significance of the results is discussed.

Original languageEnglish
Pages (from-to)985-993
Number of pages9
JournalSpectrochimica Acta Part A: Molecular Spectroscopy
Volume49
Issue number7
DOIs
Publication statusPublished - 01-01-1993

Fingerprint

Electronic structure
Fluorescence
Orbital calculations
Molecules
Molecular orbitals
Time measurement
Excited states

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

@article{ba5425cc70af4d8da7af91b0dd4b0683,
title = "Electronic structures and spectra of 6-mercaptopurine and 6-thioguanine",
abstract = "Ultraviolet absorption, steady-state fluorescence and excitation spectra of 6-mercaptopurine (6MP) and 6-(thioguanine) (6TG) have been studied, and excited state life-time measurements on their fluorescence performed. The experimental results have been interpreted with the help of molecular orbital calculations. The study shows that these molecules predominantly exist in thione forms. The properties of the molecules have been compared with those of guanine and the possible significance of the results is discussed.",
author = "C. Santhosh and Mishra, {P. C.}",
year = "1993",
month = "1",
day = "1",
doi = "10.1016/0584-8539(93)80217-X",
language = "English",
volume = "49",
pages = "985--993",
journal = "Spectrochimica Acta - Part A Molecular Spectroscopy",
issn = "0584-8539",
publisher = "Pergamon Press Ltd.",
number = "7",

}

Electronic structures and spectra of 6-mercaptopurine and 6-thioguanine. / Santhosh, C.; Mishra, P. C.

In: Spectrochimica Acta Part A: Molecular Spectroscopy, Vol. 49, No. 7, 01.01.1993, p. 985-993.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Electronic structures and spectra of 6-mercaptopurine and 6-thioguanine

AU - Santhosh, C.

AU - Mishra, P. C.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Ultraviolet absorption, steady-state fluorescence and excitation spectra of 6-mercaptopurine (6MP) and 6-(thioguanine) (6TG) have been studied, and excited state life-time measurements on their fluorescence performed. The experimental results have been interpreted with the help of molecular orbital calculations. The study shows that these molecules predominantly exist in thione forms. The properties of the molecules have been compared with those of guanine and the possible significance of the results is discussed.

AB - Ultraviolet absorption, steady-state fluorescence and excitation spectra of 6-mercaptopurine (6MP) and 6-(thioguanine) (6TG) have been studied, and excited state life-time measurements on their fluorescence performed. The experimental results have been interpreted with the help of molecular orbital calculations. The study shows that these molecules predominantly exist in thione forms. The properties of the molecules have been compared with those of guanine and the possible significance of the results is discussed.

UR - http://www.scopus.com/inward/record.url?scp=0007437765&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0007437765&partnerID=8YFLogxK

U2 - 10.1016/0584-8539(93)80217-X

DO - 10.1016/0584-8539(93)80217-X

M3 - Article

AN - SCOPUS:0007437765

VL - 49

SP - 985

EP - 993

JO - Spectrochimica Acta - Part A Molecular Spectroscopy

JF - Spectrochimica Acta - Part A Molecular Spectroscopy

SN - 0584-8539

IS - 7

ER -