Electroporation

Application in Biology and Medicine

S. B. Tiwari, D. Shenoy, N. Udupa

Research output: Contribution to journalReview article

Abstract

Electroporation is a phenomenon where a cell membrane is temporarily made permeable exposure to an intense electric field. It is a physical method primarily used for introducing genes into wide array of cell types, both eukaryotic and prokaryotic, including animal cells, plant cells, unicellular organisms such as algae or yeast, parasites and bacteria. Besides genes, electroporation can also be applied to introduce other types of molecules into cells ranging from small ions such as calcium to large molecules such as proteins, enzymes, antibodies and drugs. Recently, it has been used as a clinical tool for targeting and enhancing uptake of chemotherapeutic agents by tumours and also as a non-invasive means to enhance transdermal transport of drugs. This article briefly reviews the technique of electroporation and its major applications in biology and medicine.

Original languageEnglish
Pages (from-to)245-252
Number of pages8
JournalIndian Journal of Pharmaceutical Sciences
Volume62
Issue number4
Publication statusPublished - 07-2000

Fingerprint

Electroporation
Medicine
Prokaryotic Cells
Plant Cells
Eukaryotic Cells
Pharmaceutical Preparations
Genes
Parasites
Yeasts
Cell Membrane
Ions
Calcium
Bacteria
Antibodies
Enzymes
Neoplasms
Proteins

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Tiwari, S. B. ; Shenoy, D. ; Udupa, N. / Electroporation : Application in Biology and Medicine. In: Indian Journal of Pharmaceutical Sciences. 2000 ; Vol. 62, No. 4. pp. 245-252.
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Electroporation : Application in Biology and Medicine. / Tiwari, S. B.; Shenoy, D.; Udupa, N.

In: Indian Journal of Pharmaceutical Sciences, Vol. 62, No. 4, 07.2000, p. 245-252.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Electroporation

T2 - Application in Biology and Medicine

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AU - Shenoy, D.

AU - Udupa, N.

PY - 2000/7

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