Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study

N. Ananth, B. Balaji Ganesh, D. M. Vasudevan, Vivian D. Souza, Ashalatha V. Rao, Dinesh Nambiar

Research output: Contribution to journalArticle

Abstract

In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.

Original languageEnglish
Pages (from-to)126-128
Number of pages3
JournalIndian Journal of Clinical Biochemistry
Volume13
Issue number2
DOIs
Publication statusPublished - 01-01-1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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