Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study

N. Ananth, B. Balaji Ganesh, D. M. Vasudevan, Vivian D. Souza, Ashalatha V. Rao, Dinesh Nambiar

Research output: Contribution to journalArticle

Abstract

In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.

Original languageEnglish
Pages (from-to)126-128
Number of pages3
JournalIndian Journal of Clinical Biochemistry
Volume13
Issue number2
DOIs
Publication statusPublished - 01-01-1998
Externally publishedYes

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Protective Agents
Mouth Neoplasms
Radiotherapy
Granulocyte-Macrophage Colony-Stimulating Factor
Peroxidase
Enzyme activity
Inflammation
Enzymes

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Ananth, N. ; Balaji Ganesh, B. ; Vasudevan, D. M. ; Souza, Vivian D. ; Rao, Ashalatha V. ; Nambiar, Dinesh. / Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study. In: Indian Journal of Clinical Biochemistry. 1998 ; Vol. 13, No. 2. pp. 126-128.
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Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study. / Ananth, N.; Balaji Ganesh, B.; Vasudevan, D. M.; Souza, Vivian D.; Rao, Ashalatha V.; Nambiar, Dinesh.

In: Indian Journal of Clinical Biochemistry, Vol. 13, No. 2, 01.01.1998, p. 126-128.

Research output: Contribution to journalArticle

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