Escitalopram induced SIADH in an elderly female: A case study

Sudha Vidyasagar, Karthik Rao, Muralidhar Verma, Aswini Dutt Tripuraneni, Navin Patil, Dipanjan Bhattacharjee

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Abstract

Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders. Here, we report a case where a 58 year old diabetic lady, when initiated on escitalopram for dysthymia developed severe hyponatraemia within 2 weeks. Further, we discuss other relevant cases that have been reported in the past with an eye on the management of SIADH and hyponatraemia.

Original languageEnglish
Pages (from-to)64-67
Number of pages4
JournalPsychopharmacology Bulletin
Volume47
Issue number4
Publication statusPublished - 01-01-2017

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All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Pharmacology (medical)

Cite this

Vidyasagar, S., Rao, K., Verma, M., Tripuraneni, A. D., Patil, N., & Bhattacharjee, D. (2017). Escitalopram induced SIADH in an elderly female: A case study. Psychopharmacology Bulletin, 47(4), 64-67.