Essential thrombocythemia with portal vein thrombosis and splenic infarction successfully treated with platelet apheresis

Ami Mehul Mehta, Shubha Seshadri, Seemitr Verma, Sharath P. Madhyastha

Research output: Contribution to journalArticlepeer-review

Abstract

A 63-year-old diabetic woman presented to the outpatient clinic with a 1-week history of abdominal pain. On complete evaluation, she was diagnosed to have essential thrombocythemia. Abdominal imaging revealed portal vein thrombosis with a large splenic infarct. The patient was started on anticoagulant, antiplatelet and cytoreductive therapy. In view of persistent high platelet count, plasma apheresis was done, following which the patient's platelet counts were reduced. Essential thrombocythemia has a high rate of complications, resulting in significant morbidity and mortality. Few cases of this disease and its treatment have been described in the literature, especially pertaining to the Indian scenario. Further studies are needed to establish a multidisciplinary algorithm for its diagnosis and to elucidate the guidelines for the successful treatment of the condition.

Original languageEnglish
JournalBMJ Case Reports
Volume14
Issue number9
DOIs
Publication statusPublished - 20-09-2021

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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