Evaluation of Ammannia baccifera Linn. for antiurolithic activity in albino rats

K. V.S.R.G. Prasad, K. Bharathi, K. K. Srinivasan

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26 Citations (Scopus)

Abstract

Ethanolic extract of A. baccifera was tested for its antiurolithic activity in male albino rats. Urinary stones were induced by implantation of zinc discs in the urinary bladder. The stones formed were mainly of magnesium ammonium phosphate with traces of calcium oxalate. Ethanolic extract of A. baccifera (2 g/kg/day, po) was found to be effective in reduciug the formation of stones as also in dissolving the pre-formed ones. There was a significant increase in the urinary excretion of calcium, magnesium and oxalate, four weeks after implantation of zinc discs. Treatment with A. baccifera has significantly reduced calcium and magnesium levels in the prophylactic group while it has reversed the levels of these ions to normal values in the curative group.

Original languageEnglish
Pages (from-to)311-313
Number of pages3
JournalIndian Journal of Experimental Biology
Volume32
Issue number5
Publication statusPublished - 01-01-1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Molecular Biology
  • Cell Biology

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    Prasad, K. V. S. R. G., Bharathi, K., & Srinivasan, K. K. (1994). Evaluation of Ammannia baccifera Linn. for antiurolithic activity in albino rats. Indian Journal of Experimental Biology, 32(5), 311-313.