Evaluation of FEW ciprofloxacin (CIP) AND norfloxacin (NOR) formulations

N. Udupa, Leelavathi Bhat

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Formulations containing ciprofloxacin hydrochloride and norfloxacin for the treatment of ophthalmic and skin infections were made. The stability, bioavailability and therapeutic efficacy of the preparations were evaluated. These antibiotics were not systematically absorbed, when applied locally. Preparations were found more effective for the treatment of skin and eye infections. Betacyclodextrin improved the bioavailability of antibiotics.

Original languageEnglish
Pages (from-to)2197-2205
Number of pages9
JournalDrug Development and Industrial Pharmacy
Volume18
Issue number20
DOIs
Publication statusPublished - 1992

All Science Journal Classification (ASJC) codes

  • Drug Discovery
  • Pharmacology
  • Organic Chemistry
  • Molecular Medicine

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