Evaluation of instant desensitization after a single topical application over 30 days

A randomized trial

S. R. Samuel, S. G. Khatri, S. Acharya, S. T. Patil

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background The aim of this study was to evaluate the efficacy of ProArgin (8% arginine), Gluma® and NovaMin® (5% calcium phosphosilicate) in relieving dentinal hypersensitivity immediately and over 30 days following a single topical application. Methods A three-cell, parallel group randomized trial was conducted among 56 patients exhibiting dentinal hypersensitivity with tooth as the unit of study. ProArgin paste, Gluma® Desensitizer and NovaMin® paste were applied on randomly assigned teeth in each participant. Three stimuli were tested: tactile stimulated by running an explorer and measured using VAS (1-10 scale); air blast and cold water stimulated hypersensitivity measured using the Schiff Sensitivity Scale at baseline, immediately, 15 days and 30 days after application. Friedman test and Wilcoxon test were used for within group comparisons. Kruskal-Wallis test and Mann-Whitney U test were used for between group comparisons. Results All three groups showed significant reductions in hypersensitivity from baseline at all time points (p < 0.05). ProArgin paste elicited a significantly higher reduction in hypersensitivity (p < 0.016) compared to Gluma® and NovaMin® for all stimuli at the end of 30 days. Conclusions A single topical application of ProArgin paste is significantly more effective than both a single topical application of Gluma® and NovaMin® paste in relieving dentinal hypersensitivity immediately and over 30 days.

Original languageEnglish
Pages (from-to)336-342
Number of pages7
JournalAustralian Dental Journal
Volume60
Issue number3
DOIs
Publication statusPublished - 01-01-2015

Fingerprint

Ointments
Hypersensitivity
Tooth
Touch
Nonparametric Statistics
Arginine
Air
Calcium
NovaMin
Water
Gluma

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

Cite this

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abstract = "Background The aim of this study was to evaluate the efficacy of ProArgin™ (8{\%} arginine), Gluma{\circledR} and NovaMin{\circledR} (5{\%} calcium phosphosilicate) in relieving dentinal hypersensitivity immediately and over 30 days following a single topical application. Methods A three-cell, parallel group randomized trial was conducted among 56 patients exhibiting dentinal hypersensitivity with tooth as the unit of study. ProArgin™ paste, Gluma{\circledR} Desensitizer and NovaMin{\circledR} paste were applied on randomly assigned teeth in each participant. Three stimuli were tested: tactile stimulated by running an explorer and measured using VAS (1-10 scale); air blast and cold water stimulated hypersensitivity measured using the Schiff Sensitivity Scale at baseline, immediately, 15 days and 30 days after application. Friedman test and Wilcoxon test were used for within group comparisons. Kruskal-Wallis test and Mann-Whitney U test were used for between group comparisons. Results All three groups showed significant reductions in hypersensitivity from baseline at all time points (p < 0.05). ProArgin™ paste elicited a significantly higher reduction in hypersensitivity (p < 0.016) compared to Gluma{\circledR} and NovaMin{\circledR} for all stimuli at the end of 30 days. Conclusions A single topical application of ProArgin™ paste is significantly more effective than both a single topical application of Gluma{\circledR} and NovaMin{\circledR} paste in relieving dentinal hypersensitivity immediately and over 30 days.",
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Evaluation of instant desensitization after a single topical application over 30 days : A randomized trial. / Samuel, S. R.; Khatri, S. G.; Acharya, S.; Patil, S. T.

In: Australian Dental Journal, Vol. 60, No. 3, 01.01.2015, p. 336-342.

Research output: Contribution to journalArticle

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