Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats

B.S. Ashok Kumar, L. Deepa, K. Lakshman, K.V. Satish, K.B. Chandra Shekar, V.B. Narayan Swamy

Research output: Contribution to journalArticle

Abstract

Chitrakadi vati is well known ayurvedic formulation widely used for the treatment of constipation. So there is scientific validation the present study was evaluation of laxative activity of aqueous extract of Chitrakadi vati in rats. Laxative activity was assessed by increase in weight of faecal out put at 8 and 16th after the administration of extract. Senna was used as reference standard. The results of the study revealed that, the Chitrakadi vati exhibited significant laxative activity. This study thus justifies the traditional use of the Chitrakadi vati.
Original languageEnglish
Pages (from-to)420-423
Number of pages4
JournalPharmacologyonline
Volume1
Publication statusPublished - 2007
Externally publishedYes

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Laxatives
Validation Studies
Constipation
Weights and Measures

Cite this

Ashok Kumar, B. S., Deepa, L., Lakshman, K., Satish, K. V., Chandra Shekar, K. B., & Narayan Swamy, V. B. (2007). Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. Pharmacologyonline, 1, 420-423.
Ashok Kumar, B.S. ; Deepa, L. ; Lakshman, K. ; Satish, K.V. ; Chandra Shekar, K.B. ; Narayan Swamy, V.B. / Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. In: Pharmacologyonline. 2007 ; Vol. 1. pp. 420-423.
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title = "Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats",
abstract = "Chitrakadi vati is well known ayurvedic formulation widely used for the treatment of constipation. So there is scientific validation the present study was evaluation of laxative activity of aqueous extract of Chitrakadi vati in rats. Laxative activity was assessed by increase in weight of faecal out put at 8 and 16th after the administration of extract. Senna was used as reference standard. The results of the study revealed that, the Chitrakadi vati exhibited significant laxative activity. This study thus justifies the traditional use of the Chitrakadi vati.",
author = "{Ashok Kumar}, B.S. and L. Deepa and K. Lakshman and K.V. Satish and {Chandra Shekar}, K.B. and {Narayan Swamy}, V.B.",
note = "Export Date: 10 November 2017 Correspondence Address: Ashok Kumar, B.S.; Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka, India References: Yoga Ratnavali, V., The Indian medical practitioners Cooperative Pharmacy and Stores Ltd, pp. 55-57. , 4th edn. Madras, p; Nadkarni KM and Nadkarni AK. Indian Materia Medica, I, 3rd edn. M/s Popular Prakashan Pvt, Ltd., Bombay, 1999; p965, 990; Yoganarasimhan, S.N., (2000) Medicinal Plant of India, 2, p. 426. , Tamilnadu; Capasso, F., Mascolo, N., Autore, G., Romano, V., (1986) Journal of Pharmaceutical Phamacology, 13, p. 627; Ganapaty, S., Subburaju, T., Dash, G.K., Suresh, B., Diuretic, Laxative and Toxicity studies of Cocculus hirsutus aerial parts (2002) Fitoterapia, 73, pp. 28-31; Goodman, Gilmann, (2001) The Pharmacological Basis of Therapeutics, pp. 1045-1046. , 10th edn. McGraw-Hill, Medical Publishing Division, New York, pp",
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Ashok Kumar, BS, Deepa, L, Lakshman, K, Satish, KV, Chandra Shekar, KB & Narayan Swamy, VB 2007, 'Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats', Pharmacologyonline, vol. 1, pp. 420-423.

Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. / Ashok Kumar, B.S.; Deepa, L.; Lakshman, K.; Satish, K.V.; Chandra Shekar, K.B.; Narayan Swamy, V.B.

In: Pharmacologyonline, Vol. 1, 2007, p. 420-423.

Research output: Contribution to journalArticle

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AB - Chitrakadi vati is well known ayurvedic formulation widely used for the treatment of constipation. So there is scientific validation the present study was evaluation of laxative activity of aqueous extract of Chitrakadi vati in rats. Laxative activity was assessed by increase in weight of faecal out put at 8 and 16th after the administration of extract. Senna was used as reference standard. The results of the study revealed that, the Chitrakadi vati exhibited significant laxative activity. This study thus justifies the traditional use of the Chitrakadi vati.

M3 - Article

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JO - Pharmacologyonline

JF - Pharmacologyonline

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Ashok Kumar BS, Deepa L, Lakshman K, Satish KV, Chandra Shekar KB, Narayan Swamy VB. Evaluation of laxative activity of Chitrakadi vati, an ayurvedic formulation in rats. Pharmacologyonline. 2007;1:420-423.