Abstract
Recent attention has been directed towards the role of mast cells in the pathogenesis of oral lichen planus. Mast cells are responsible for trafficking of inflammatory cells into the connective tissue that in turn helps in progression and maintenance of the chronicity of oral lichen planus. In the present study we have evaluated the mast cell count and its cell types using toluidine blue stain, in oral lichen planus and compared it with oral lichenoid reactions. We have observed an increase in mast cell count in both these conditions in comparison to normal mucosa. Also, a significant difference in the types of mast cells in oral lichen planus and oral lichenoid reactions has been noted, possibly suggesting that the role of mast cell is different in these conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 175-179 |
| Number of pages | 5 |
| Journal | Indian journal of dental research : official publication of Indian Society for Dental Research |
| Volume | 12 |
| Issue number | 3 |
| Publication status | Published - 07-2001 |
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All Science Journal Classification (ASJC) codes
- Dentistry(all)
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Evaluation of mast cells in oral lichen planus and oral lichenoid reaction. / Jose, M.; Raghu, A. R.; Rao, N. N.
In: Indian journal of dental research : official publication of Indian Society for Dental Research, Vol. 12, No. 3, 07.2001, p. 175-179.Research output: Contribution to journal › Article
TY - JOUR
T1 - Evaluation of mast cells in oral lichen planus and oral lichenoid reaction.
AU - Jose, M.
AU - Raghu, A. R.
AU - Rao, N. N.
PY - 2001/7
Y1 - 2001/7
N2 - Recent attention has been directed towards the role of mast cells in the pathogenesis of oral lichen planus. Mast cells are responsible for trafficking of inflammatory cells into the connective tissue that in turn helps in progression and maintenance of the chronicity of oral lichen planus. In the present study we have evaluated the mast cell count and its cell types using toluidine blue stain, in oral lichen planus and compared it with oral lichenoid reactions. We have observed an increase in mast cell count in both these conditions in comparison to normal mucosa. Also, a significant difference in the types of mast cells in oral lichen planus and oral lichenoid reactions has been noted, possibly suggesting that the role of mast cell is different in these conditions.
AB - Recent attention has been directed towards the role of mast cells in the pathogenesis of oral lichen planus. Mast cells are responsible for trafficking of inflammatory cells into the connective tissue that in turn helps in progression and maintenance of the chronicity of oral lichen planus. In the present study we have evaluated the mast cell count and its cell types using toluidine blue stain, in oral lichen planus and compared it with oral lichenoid reactions. We have observed an increase in mast cell count in both these conditions in comparison to normal mucosa. Also, a significant difference in the types of mast cells in oral lichen planus and oral lichenoid reactions has been noted, possibly suggesting that the role of mast cell is different in these conditions.
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UR - http://www.scopus.com/inward/citedby.url?scp=0035411181&partnerID=8YFLogxK
M3 - Article
VL - 12
SP - 175
EP - 179
JO - Indian Journal of Dental Research
JF - Indian Journal of Dental Research
SN - 0970-9290
IS - 3
ER -