Evaluation of potentiation effect of omega-3 fatty acid on the antidepressant efficacy of escitalopram in albino rats

Amberkar Mohanbabu Vittalrao, Saurabh Agarwal, Meena Kumari Kamalkishore, Basavaraj Poojar

Research output: Contribution to journalArticle

Abstract

Depression is a common problem worldwide since the ages.Mostly it is treated with Selective serotonin reuptake inhibitors (SSRI) but they are not effective in each and every patient. Hence other methods for better effective ways to treat depression are needed. Our study thus aims at studying the potentiation effect of omega-3 fatty acid in combination with escitalopram for treatment of depression. Combination therapy also helps to reduce side effects of SSRIs and a lower dose can be used in children and pregnant mothers. Various animal models have been used in this pre-clinical study to study the effect of omega-3 fatty acids. Further clinical studies may be required to validate the results of this study.

Original languageEnglish
Pages (from-to)1471-1480
Number of pages10
JournalBiomedical and Pharmacology Journal
Volume12
Issue number3
DOIs
Publication statusPublished - 01-01-2019

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Citalopram
Omega-3 Fatty Acids
Antidepressive Agents
Depression
Serotonin Uptake Inhibitors
Animal Models
Mothers
Therapeutics
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Pharmacology

Cite this

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Evaluation of potentiation effect of omega-3 fatty acid on the antidepressant efficacy of escitalopram in albino rats. / Vittalrao, Amberkar Mohanbabu; Agarwal, Saurabh; Kamalkishore, Meena Kumari; Poojar, Basavaraj.

In: Biomedical and Pharmacology Journal, Vol. 12, No. 3, 01.01.2019, p. 1471-1480.

Research output: Contribution to journalArticle

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