Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI)

P. Adhikari, B. M. Hegde, P. Pereira, P. Bhat, N. Chowta, K. V. Ramesh, T. V. Venkatadri, M. M. Pai

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Azithromycin was given to 55 cases of lower respiratory tract infections in the doses of 500 mg on day 1, followed by 250 mg on days 2-5. It produced bacteriological cure in 70.8% patients and clinical cure or improvement in 69.09% of patients. 4.27% of patients had throat colonisation with new organisms, of which 9.09% needed a second antibiotic. The drug was well tolerated and minor side effects were noted. Gastrointestinal disturbances (16.36%) headache and giddiness (14.55%), rash (3.64%) were the noted side effects. Reduction of platelet count by 50% occurred in 12.29% of the cases compared to 0.2% reported earlier. But this thrombocytopenia was clinically not significant, as it did not cause any symptoms.

Original languageEnglish
Pages (from-to)313-317
Number of pages5
JournalIndian Journal of Medical Sciences
Volume50
Issue number9
Publication statusPublished - 01-09-1996

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Azithromycin
Respiratory Tract Infections
Safety
Dizziness
Pharynx
Exanthema
Platelet Count
Thrombocytopenia
Headache
Anti-Bacterial Agents
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Adhikari, P. ; Hegde, B. M. ; Pereira, P. ; Bhat, P. ; Chowta, N. ; Ramesh, K. V. ; Venkatadri, T. V. ; Pai, M. M. / Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI). In: Indian Journal of Medical Sciences. 1996 ; Vol. 50, No. 9. pp. 313-317.
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Adhikari, P, Hegde, BM, Pereira, P, Bhat, P, Chowta, N, Ramesh, KV, Venkatadri, TV & Pai, MM 1996, 'Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI)', Indian Journal of Medical Sciences, vol. 50, no. 9, pp. 313-317.

Evaluation of safety and efficacy of azithromycin in lower respiratory tract infections (LRTI). / Adhikari, P.; Hegde, B. M.; Pereira, P.; Bhat, P.; Chowta, N.; Ramesh, K. V.; Venkatadri, T. V.; Pai, M. M.

In: Indian Journal of Medical Sciences, Vol. 50, No. 9, 01.09.1996, p. 313-317.

Research output: Contribution to journalArticle

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