Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

P. Pragathi; P. V. Bharath Kumar; P. Amar Kumar; M. Ramakanth Reddy; V. Sravani; J. Neeraja; Reeba Mary Eapen; K. Gopalakrishna

doi:10.1007/BF02867428

Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

P. Pragathi, P. V. Bharath Kumar, P. Amar Kumar, M. Ramakanth Reddy, V. Sravani, J. Neeraja, Reeba Mary Eapen, K. Gopalakrishna

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

Original language	English
Pages (from-to)	195-197
Number of pages	3
Journal	Indian Journal of Clinical Biochemistry
Volume	20
Issue number	2
DOIs	https://doi.org/10.1007/BF02867428
Publication status	Published - 01-01-2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF02867428

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title = "Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer",

abstract = "Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.",

author = "P. Pragathi and {Bharath Kumar}, {P. V.} and {Amar Kumar}, P. and {Ramakanth Reddy}, M. and V. Sravani and J. Neeraja and Eapen, {Reeba Mary} and K. Gopalakrishna",

year = "2005",

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doi = "10.1007/BF02867428",

language = "English",

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TY - JOUR

T1 - Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

AU - Pragathi, P.

AU - Bharath Kumar, P. V.

AU - Amar Kumar, P.

AU - Ramakanth Reddy, M.

AU - Sravani, V.

AU - Neeraja, J.

AU - Eapen, Reeba Mary

AU - Gopalakrishna, K.

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

AB - Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

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Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

Abstract

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