Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

P. Pragathi, P. V. Bharath Kumar, P. Amar Kumar, M. Ramakanth Reddy, V. Sravani, J. Neeraja, Reeba Mary Eapen, K. Gopalakrishna

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Abstract

Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

Original languageEnglish
Pages (from-to)195-197
Number of pages3
JournalIndian Journal of Clinical Biochemistry
Volume20
Issue number2
DOIs
Publication statusPublished - 01-01-2005
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Pragathi, P., Bharath Kumar, P. V., Amar Kumar, P., Ramakanth Reddy, M., Sravani, V., Neeraja, J., ... Gopalakrishna, K. (2005). Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer. Indian Journal of Clinical Biochemistry, 20(2), 195-197. https://doi.org/10.1007/BF02867428