Evaluation of supportive care management outcomes in cancer chemotherapy: A prospective observational study in a tertiary care teaching hospital in South India

Reshma Reji, Binit Kumar, N. Sreedharan, Girish Thunga, K. Vijayanarayana, Mahadev Rao, Karthik Udupa, M. Unnikrishnan

Research output: Contribution to journalArticle

Abstract

Aims: Evaluation of supportive care management of cancer patients experiencing drug-related problems (DRPs) is a challenge because it might increase the cost due to additional therapy. The main objectives of this study were to estimate chemotherapy-associated drug-related hospital admissions in the department of medical oncology and to estimate the cost of managing chemotherapy-associated DRPs. Settings and Design: This study is a prospective observational study. Subjects and Methods: Patients with chemotherapy-related DRPs were prospectively identified from the patient's medical records. The contribution of DRPs and cost incurred due to each hospitalization was assessed. Statistical Analysis Used: Data were analyzed using SPSS® 20.0 version. Results: Out of 55 patients analyzed for DRPs, 25 (45.5%) patients in the age group of 51-60 years experienced DRPs most frequently. Most commonly occurring DRP was adverse drug reactions 42 (76.4%), which were more frequent in females. DRPs were maximum with alkylating agents 15 (27.3%) and the least with hormonal agents 1 (1.8%). The mean length of hospitalization was 9.6 ± 6.5 days. The total direct medical cost was Rs. 31,540 ± 42,476, of which medicine cost accounted for Rs. 16,550 ± 25,404, constituting a major share of the total medical costs. Conclusions: Pharmacists can provide better patient care by identifying and preventing DRPs and reducing drug-related morbidity and mortality.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalIndian Journal of Palliative Care
Volume24
Issue number2
DOIs
Publication statusPublished - 01-04-2018

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Tertiary Healthcare
Teaching Hospitals
Observational Studies
India
Prospective Studies
Drug Therapy
Pharmaceutical Preparations
Neoplasms
Costs and Cost Analysis
Hospitalization
Patient Care Management
Statistical Data Interpretation
Medical Oncology
Alkylating Agents
Drug-Related Side Effects and Adverse Reactions
Pharmacists
Medical Records
Patient Care
Age Groups
Medicine

All Science Journal Classification (ASJC) codes

  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

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title = "Evaluation of supportive care management outcomes in cancer chemotherapy: A prospective observational study in a tertiary care teaching hospital in South India",
abstract = "Aims: Evaluation of supportive care management of cancer patients experiencing drug-related problems (DRPs) is a challenge because it might increase the cost due to additional therapy. The main objectives of this study were to estimate chemotherapy-associated drug-related hospital admissions in the department of medical oncology and to estimate the cost of managing chemotherapy-associated DRPs. Settings and Design: This study is a prospective observational study. Subjects and Methods: Patients with chemotherapy-related DRPs were prospectively identified from the patient's medical records. The contribution of DRPs and cost incurred due to each hospitalization was assessed. Statistical Analysis Used: Data were analyzed using SPSS{\circledR} 20.0 version. Results: Out of 55 patients analyzed for DRPs, 25 (45.5{\%}) patients in the age group of 51-60 years experienced DRPs most frequently. Most commonly occurring DRP was adverse drug reactions 42 (76.4{\%}), which were more frequent in females. DRPs were maximum with alkylating agents 15 (27.3{\%}) and the least with hormonal agents 1 (1.8{\%}). The mean length of hospitalization was 9.6 ± 6.5 days. The total direct medical cost was Rs. 31,540 ± 42,476, of which medicine cost accounted for Rs. 16,550 ± 25,404, constituting a major share of the total medical costs. Conclusions: Pharmacists can provide better patient care by identifying and preventing DRPs and reducing drug-related morbidity and mortality.",
author = "Reshma Reji and Binit Kumar and N. Sreedharan and Girish Thunga and K. Vijayanarayana and Mahadev Rao and Karthik Udupa and M. Unnikrishnan",
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AU - Reji, Reshma

AU - Kumar, Binit

AU - Sreedharan, N.

AU - Thunga, Girish

AU - Vijayanarayana, K.

AU - Rao, Mahadev

AU - Udupa, Karthik

AU - Unnikrishnan, M.

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