Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats

B. S. Nayak, B. Vinutha, B. Geetha, B. Sudha

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg- 1 day- 1 for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.

Original languageEnglish
Pages (from-to)671-675
Number of pages5
JournalFitoterapia
Volume76
Issue number7-8
DOIs
Publication statusPublished - 01-12-2005
Externally publishedYes

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Rubiaceae
Wound Healing
Granulation Tissue
Tensile Strength
Hydroxyproline
Wounds and Injuries
Glycosaminoglycans
Collagen
Weights and Measures
Proteins

All Science Journal Classification (ASJC) codes

  • Pharmacology

Cite this

Nayak, B. S. ; Vinutha, B. ; Geetha, B. ; Sudha, B. / Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats. In: Fitoterapia. 2005 ; Vol. 76, No. 7-8. pp. 671-675.
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Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats. / Nayak, B. S.; Vinutha, B.; Geetha, B.; Sudha, B.

In: Fitoterapia, Vol. 76, No. 7-8, 01.12.2005, p. 671-675.

Research output: Contribution to journalArticle

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