Factors affecting the nasal carriage of methicillin-resistant Staphylococcus aureus in human immunodeficiency virus-infected patients

J. Chacko, M. Kuruvila, G. Bhat

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16 Citations (Scopus)

Abstract

Human immunodeficiency virus-infected patients attending skin outpatient department were studied for nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) and associated factors affecting nasal colonization. Nasal swabs were used for isolation of S. aureus. MRSA were detected by agar screen and agar dilution methods. Careful examination for dermatoses was carried out. Forty-six of the 60 (76.67%) outpatients with HIV infection were colonized with S. aureus in the anterior nares. Significant number of S. aureus carriers were in the 31-40 year age group. Methicillin resistance was found in eight (17.39%) isolates. Of the 46 S. aureus strains, 29 (63%) were resistant to erythromycin, 69.5% to co-trimoxazole and 41.3% to ciprofloxacin. Co-trimoxazole use was found to be a risk factor for S. aureus carriage ( P = 0.0214) but not for methicillin resistance. Hospital stay for more than 10 days was a risk factor for methicillin resistance whereas stay for more than 25 days was found to be a highly significant risk factor. Dermatophytosis and herpes simplex virus infection were other risk factors for nasal carriage of S. aureus.

Original languageEnglish
Pages (from-to)146-148
Number of pages3
JournalIndian Journal of Medical Microbiology
Volume27
Issue number2
DOIs
Publication statusPublished - 01-04-2009

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Methicillin-Resistant Staphylococcus aureus
Nose
Staphylococcus aureus
HIV
Methicillin Resistance
Sulfamethoxazole Drug Combination Trimethoprim
Agar
Outpatients
Tinea
Virus Diseases
Simplexvirus
Erythromycin
Ciprofloxacin
Skin Diseases
HIV Infections
Length of Stay
Age Groups
Skin

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)

Cite this

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abstract = "Human immunodeficiency virus-infected patients attending skin outpatient department were studied for nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) and associated factors affecting nasal colonization. Nasal swabs were used for isolation of S. aureus. MRSA were detected by agar screen and agar dilution methods. Careful examination for dermatoses was carried out. Forty-six of the 60 (76.67{\%}) outpatients with HIV infection were colonized with S. aureus in the anterior nares. Significant number of S. aureus carriers were in the 31-40 year age group. Methicillin resistance was found in eight (17.39{\%}) isolates. Of the 46 S. aureus strains, 29 (63{\%}) were resistant to erythromycin, 69.5{\%} to co-trimoxazole and 41.3{\%} to ciprofloxacin. Co-trimoxazole use was found to be a risk factor for S. aureus carriage ( P = 0.0214) but not for methicillin resistance. Hospital stay for more than 10 days was a risk factor for methicillin resistance whereas stay for more than 25 days was found to be a highly significant risk factor. Dermatophytosis and herpes simplex virus infection were other risk factors for nasal carriage of S. aureus.",
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