Factors associated with neonatal pneumonia in India: Protocol for a systematic review and planned meta-analysis

Sreekumaran Nair, Leslie Edward Lewis, Myron Anthony Godinho, Shruti Murthy, Theophilus Lakiang, Bhumika T. Venkatesh

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Introduction India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India. English language observational studies which report risk factors and determinants of neonatal pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using 'Assessing the Methodological quality of Systematic Reviews' and Grades of Recommendation, Assessment, Development and Evaluation'. Ethics and dissemination The protocol of the entire project has been approved by the host institution's ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the â Health Ministry Screening Committee' under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.

Original languageEnglish
Article numbere018790
JournalBMJ Open
Volume8
Issue number1
DOIs
Publication statusPublished - 01-01-2018

Fingerprint

Meta-Analysis
India
Pneumonia
Ethics
Newborn Infant
Publication Bias
Ethics Committees
Family Health
Observational Studies
Publications
Language
Databases
Education
Health

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Nair, Sreekumaran ; Lewis, Leslie Edward ; Godinho, Myron Anthony ; Murthy, Shruti ; Lakiang, Theophilus ; Venkatesh, Bhumika T. / Factors associated with neonatal pneumonia in India : Protocol for a systematic review and planned meta-analysis. In: BMJ Open. 2018 ; Vol. 8, No. 1.
@article{0276a3d20653497f802cda4655731627,
title = "Factors associated with neonatal pneumonia in India: Protocol for a systematic review and planned meta-analysis",
abstract = "Introduction India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India. English language observational studies which report risk factors and determinants of neonatal pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using 'Assessing the Methodological quality of Systematic Reviews' and Grades of Recommendation, Assessment, Development and Evaluation'. Ethics and dissemination The protocol of the entire project has been approved by the host institution's ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the {\^a} Health Ministry Screening Committee' under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.",
author = "Sreekumaran Nair and Lewis, {Leslie Edward} and Godinho, {Myron Anthony} and Shruti Murthy and Theophilus Lakiang and Venkatesh, {Bhumika T.}",
year = "2018",
month = "1",
day = "1",
doi = "10.1136/bmjopen-2017-018790",
language = "English",
volume = "8",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "BMJ Publishing Group",
number = "1",

}

Factors associated with neonatal pneumonia in India : Protocol for a systematic review and planned meta-analysis. / Nair, Sreekumaran; Lewis, Leslie Edward; Godinho, Myron Anthony; Murthy, Shruti; Lakiang, Theophilus; Venkatesh, Bhumika T.

In: BMJ Open, Vol. 8, No. 1, e018790, 01.01.2018.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Factors associated with neonatal pneumonia in India

T2 - Protocol for a systematic review and planned meta-analysis

AU - Nair, Sreekumaran

AU - Lewis, Leslie Edward

AU - Godinho, Myron Anthony

AU - Murthy, Shruti

AU - Lakiang, Theophilus

AU - Venkatesh, Bhumika T.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Introduction India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India. English language observational studies which report risk factors and determinants of neonatal pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using 'Assessing the Methodological quality of Systematic Reviews' and Grades of Recommendation, Assessment, Development and Evaluation'. Ethics and dissemination The protocol of the entire project has been approved by the host institution's ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the â Health Ministry Screening Committee' under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.

AB - Introduction India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. Methods and analysis This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India. English language observational studies which report risk factors and determinants of neonatal pneumonia in India will be eligible for inclusion. Electronic searching of nine databases, and hand searching will be done. Two authors will independently conduct screening (title, abstract and full-text stages), extract data and assess risk of bias. A meta-analysis is planned to be performed with random-effects model. A narrative synthesis will be used to summarise the characteristics and findings of the review, if a meta-analysis cannot be performed. If there are more than 10 studies, publication bias will be assessed. Sensitivity and subgroup analysis will performed based on data availability. The quality of our review will be assessed by using 'Assessing the Methodological quality of Systematic Reviews' and Grades of Recommendation, Assessment, Development and Evaluation'. Ethics and dissemination The protocol of the entire project has been approved by the host institution's ethics body (Institutional Ethics Committee, Manipal University, Manipal, India), and the â Health Ministry Screening Committee' under the Ministry of Health and Family Welfare, Government of India. The study findings will be disseminated among relevant stakeholders using knowledge dissemination workshops, policy briefs, publications, etc. PROSPERO registration number CRD42016044019.

UR - http://www.scopus.com/inward/record.url?scp=85040569539&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040569539&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2017-018790

DO - 10.1136/bmjopen-2017-018790

M3 - Review article

AN - SCOPUS:85040569539

VL - 8

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 1

M1 - e018790

ER -