Factors that correlate with poor glycemic control in type 2 diabetes mellitus patients with complications

Mohammad Haghighatpanah, Amir Sasan Mozaffari Nejad, Maryam Haghighatpanah, Girish Thunga, Surulivelrajan Mallayasamy

Research output: Contribution to journalArticle

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Abstract

Objectives: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes. Methods: This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients' HbA1c levels were categorized into good control ≤7% (≤53mmol/mol), and poor control > 7% ( > 53mmol/mol), and patients'characteristics were analyzed. Results: A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6%)], had a family history of diabetes [n = 256 (39%)] and obesity [n = 95 (14.5%)], all had poor glycemic control. Conclusion: This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications.

Original languageEnglish
Pages (from-to)167-174
Number of pages8
JournalOsong Public Health and Research Perspectives
Volume9
Issue number4
DOIs
Publication statusPublished - 01-01-2018

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Type 2 Diabetes Mellitus
Diabetes Complications
Blood Glucose
Insulin
HDL Lipoproteins
Hypoglycemic Agents
Teaching Hospitals
Medical Records
Observational Studies
India
Fasting
Outpatients
Therapeutics
Retrospective Studies
Public Health
Obesity

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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title = "Factors that correlate with poor glycemic control in type 2 diabetes mellitus patients with complications",
abstract = "Objectives: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes. Methods: This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients' HbA1c levels were categorized into good control ≤7{\%} (≤53mmol/mol), and poor control > 7{\%} ( > 53mmol/mol), and patients'characteristics were analyzed. Results: A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1{\%}) females and 505 (76.9{\%}) males, and 514 (78.2{\%}) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1{\%})], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6{\%})]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6{\%})], had a family history of diabetes [n = 256 (39{\%})] and obesity [n = 95 (14.5{\%})], all had poor glycemic control. Conclusion: This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications.",
author = "Mohammad Haghighatpanah and Nejad, {Amir Sasan Mozaffari} and Maryam Haghighatpanah and Girish Thunga and Surulivelrajan Mallayasamy",
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Factors that correlate with poor glycemic control in type 2 diabetes mellitus patients with complications. / Haghighatpanah, Mohammad; Nejad, Amir Sasan Mozaffari; Haghighatpanah, Maryam; Thunga, Girish; Mallayasamy, Surulivelrajan.

In: Osong Public Health and Research Perspectives, Vol. 9, No. 4, 01.01.2018, p. 167-174.

Research output: Contribution to journalArticle

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AU - Haghighatpanah, Mohammad

AU - Nejad, Amir Sasan Mozaffari

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AU - Thunga, Girish

AU - Mallayasamy, Surulivelrajan

PY - 2018/1/1

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