Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy

A case report

Muktha Ramesh Pai, Prabha Adhikari, Raghuveer Vasudev Rao Coimbatore, Siddique Ahmed

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems, including lymph nodes, due to the production of antinuclear antibodies. The onset of disease is between ages 13 and 40 years, with a female preponderance. CASE: A 30-year-old female presented with right cervical lymphadenopathy and gave a history of intermittent fever and swollen joints of 2.5 years' duration. The patient was on intermittent corticosteroids. With a suggestion of tuberculous lymphadenitis, the patient underwent fine needle aspiration (FNA). The diagnosis of lupus adenopathy was established by FNA of enlarged right cervical lymph nodes. Smears showed predominantly typical and atypical immunoblasts, plasma cells, occasional Reed-Sternberg-like cells and dispersed hematoxylin bodies. Smears were negative for acid-fast bacilli. CONCLUSION: When SLE patients develop lymphadenopathy, FNA cytology helps differentiate lupus adenopathy from infectious conditions, such as tuberculous adenitis, and from Kikuchi's lymphadenitis.

Original languageEnglish
Pages (from-to)67-69
Number of pages3
JournalActa Cytologica
Volume44
Issue number1
Publication statusPublished - 01-01-2000

Fingerprint

Fine Needle Biopsy
Systemic Lupus Erythematosus
Cell Biology
Lymphadenitis
Lymph Nodes
Reed-Sternberg Cells
Lymph Node Tuberculosis
Antinuclear Antibodies
Hematoxylin
Plasma Cells
Bacillus
Autoimmune Diseases
Adrenal Cortex Hormones
Fever
Joints
Inflammation
Acids
Lymphadenopathy

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

Pai, M. R., Adhikari, P., Coimbatore, R. V. R., & Ahmed, S. (2000). Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy: A case report. Acta Cytologica, 44(1), 67-69.
Pai, Muktha Ramesh ; Adhikari, Prabha ; Coimbatore, Raghuveer Vasudev Rao ; Ahmed, Siddique. / Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy : A case report. In: Acta Cytologica. 2000 ; Vol. 44, No. 1. pp. 67-69.
@article{36aa9c9e192e474b95a5c606f8817c25,
title = "Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy: A case report",
abstract = "BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems, including lymph nodes, due to the production of antinuclear antibodies. The onset of disease is between ages 13 and 40 years, with a female preponderance. CASE: A 30-year-old female presented with right cervical lymphadenopathy and gave a history of intermittent fever and swollen joints of 2.5 years' duration. The patient was on intermittent corticosteroids. With a suggestion of tuberculous lymphadenitis, the patient underwent fine needle aspiration (FNA). The diagnosis of lupus adenopathy was established by FNA of enlarged right cervical lymph nodes. Smears showed predominantly typical and atypical immunoblasts, plasma cells, occasional Reed-Sternberg-like cells and dispersed hematoxylin bodies. Smears were negative for acid-fast bacilli. CONCLUSION: When SLE patients develop lymphadenopathy, FNA cytology helps differentiate lupus adenopathy from infectious conditions, such as tuberculous adenitis, and from Kikuchi's lymphadenitis.",
author = "Pai, {Muktha Ramesh} and Prabha Adhikari and Coimbatore, {Raghuveer Vasudev Rao} and Siddique Ahmed",
year = "2000",
month = "1",
day = "1",
language = "English",
volume = "44",
pages = "67--69",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "1",

}

Pai, MR, Adhikari, P, Coimbatore, RVR & Ahmed, S 2000, 'Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy: A case report', Acta Cytologica, vol. 44, no. 1, pp. 67-69.

Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy : A case report. / Pai, Muktha Ramesh; Adhikari, Prabha; Coimbatore, Raghuveer Vasudev Rao; Ahmed, Siddique.

In: Acta Cytologica, Vol. 44, No. 1, 01.01.2000, p. 67-69.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fine needle aspiration cytology in systemic lupus erythematosus lymphadenopathy

T2 - A case report

AU - Pai, Muktha Ramesh

AU - Adhikari, Prabha

AU - Coimbatore, Raghuveer Vasudev Rao

AU - Ahmed, Siddique

PY - 2000/1/1

Y1 - 2000/1/1

N2 - BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems, including lymph nodes, due to the production of antinuclear antibodies. The onset of disease is between ages 13 and 40 years, with a female preponderance. CASE: A 30-year-old female presented with right cervical lymphadenopathy and gave a history of intermittent fever and swollen joints of 2.5 years' duration. The patient was on intermittent corticosteroids. With a suggestion of tuberculous lymphadenitis, the patient underwent fine needle aspiration (FNA). The diagnosis of lupus adenopathy was established by FNA of enlarged right cervical lymph nodes. Smears showed predominantly typical and atypical immunoblasts, plasma cells, occasional Reed-Sternberg-like cells and dispersed hematoxylin bodies. Smears were negative for acid-fast bacilli. CONCLUSION: When SLE patients develop lymphadenopathy, FNA cytology helps differentiate lupus adenopathy from infectious conditions, such as tuberculous adenitis, and from Kikuchi's lymphadenitis.

AB - BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology characterized by inflammation in various organ systems, including lymph nodes, due to the production of antinuclear antibodies. The onset of disease is between ages 13 and 40 years, with a female preponderance. CASE: A 30-year-old female presented with right cervical lymphadenopathy and gave a history of intermittent fever and swollen joints of 2.5 years' duration. The patient was on intermittent corticosteroids. With a suggestion of tuberculous lymphadenitis, the patient underwent fine needle aspiration (FNA). The diagnosis of lupus adenopathy was established by FNA of enlarged right cervical lymph nodes. Smears showed predominantly typical and atypical immunoblasts, plasma cells, occasional Reed-Sternberg-like cells and dispersed hematoxylin bodies. Smears were negative for acid-fast bacilli. CONCLUSION: When SLE patients develop lymphadenopathy, FNA cytology helps differentiate lupus adenopathy from infectious conditions, such as tuberculous adenitis, and from Kikuchi's lymphadenitis.

UR - http://www.scopus.com/inward/record.url?scp=0033959852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033959852&partnerID=8YFLogxK

M3 - Article

VL - 44

SP - 67

EP - 69

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 1

ER -