Fine needle aspiration cytology of benign fibrous histiocytoma of bone: A case report

Shankaranand Siddappa Bharatnur, Chamarajanagar Nanjanayak Ramesh Naik, Gumballi Krishnamurthy Swethadri, Hilda Fernandes, Jayaprakash Chandra Shekhar, Nisha Jayashankar Marla

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Benign fibrous histiocytoma (BFH) of bone is a very rare tumor, and almost all reported cases were diagnosed after surgical resection by histologic examination. We report a case in which cytologic features of BFH of bone were established preoperatively by fine needle aspiration (FNA). To the best of our knowledge, FNA findings of BFH of bone have not been. previously reported. Case: A 30-year-old man presented with pain in the right knee of 3 days' duration. Radiographs of the distal femur showed a lytic lesion. FNA biopsy followed by cytologic examination revealed highly cellular smears with spindle-shaped cells arranged in sheets; papillary fronds and storiform pattern. These cells had a moderate amount of cytoplasm and round to elongated nuclei with inconspicuous nucleoli. Multinucleate giant cells were occasionally seen. A cytologic diagnosis of Giant cell tumor of bone with a BFH component was rendered. Histology revealed a pure BPH of bone. Conclusion: The current case reveals the cytomorphologic features of BFH of bone. Cytology may permit the preoperative recognition of the lesion, allowing a more sound therapeutic approach.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalActa Cytologica
Volume54
Issue number1
DOIs
Publication statusPublished - 01-01-2010

Fingerprint

Benign Fibrous Histiocytoma
Fine Needle Biopsy
Cell Biology
Bone and Bones
Giant Cell Tumor of Bone
Giant Cells
Femur
Knee
Histology
Cytoplasm
Pain
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

Bharatnur, S. S., Ramesh Naik, C. N., Swethadri, G. K., Fernandes, H., Shekhar, J. C., & Marla, N. J. (2010). Fine needle aspiration cytology of benign fibrous histiocytoma of bone: A case report. Acta Cytologica, 54(1), 89-91. https://doi.org/10.1159/000324976
Bharatnur, Shankaranand Siddappa ; Ramesh Naik, Chamarajanagar Nanjanayak ; Swethadri, Gumballi Krishnamurthy ; Fernandes, Hilda ; Shekhar, Jayaprakash Chandra ; Marla, Nisha Jayashankar. / Fine needle aspiration cytology of benign fibrous histiocytoma of bone : A case report. In: Acta Cytologica. 2010 ; Vol. 54, No. 1. pp. 89-91.
@article{b24b33771cff4717b3cd3c682ae9b8b8,
title = "Fine needle aspiration cytology of benign fibrous histiocytoma of bone: A case report",
abstract = "Background: Benign fibrous histiocytoma (BFH) of bone is a very rare tumor, and almost all reported cases were diagnosed after surgical resection by histologic examination. We report a case in which cytologic features of BFH of bone were established preoperatively by fine needle aspiration (FNA). To the best of our knowledge, FNA findings of BFH of bone have not been. previously reported. Case: A 30-year-old man presented with pain in the right knee of 3 days' duration. Radiographs of the distal femur showed a lytic lesion. FNA biopsy followed by cytologic examination revealed highly cellular smears with spindle-shaped cells arranged in sheets; papillary fronds and storiform pattern. These cells had a moderate amount of cytoplasm and round to elongated nuclei with inconspicuous nucleoli. Multinucleate giant cells were occasionally seen. A cytologic diagnosis of Giant cell tumor of bone with a BFH component was rendered. Histology revealed a pure BPH of bone. Conclusion: The current case reveals the cytomorphologic features of BFH of bone. Cytology may permit the preoperative recognition of the lesion, allowing a more sound therapeutic approach.",
author = "Bharatnur, {Shankaranand Siddappa} and {Ramesh Naik}, {Chamarajanagar Nanjanayak} and Swethadri, {Gumballi Krishnamurthy} and Hilda Fernandes and Shekhar, {Jayaprakash Chandra} and Marla, {Nisha Jayashankar}",
year = "2010",
month = "1",
day = "1",
doi = "10.1159/000324976",
language = "English",
volume = "54",
pages = "89--91",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "1",

}

Bharatnur, SS, Ramesh Naik, CN, Swethadri, GK, Fernandes, H, Shekhar, JC & Marla, NJ 2010, 'Fine needle aspiration cytology of benign fibrous histiocytoma of bone: A case report', Acta Cytologica, vol. 54, no. 1, pp. 89-91. https://doi.org/10.1159/000324976

Fine needle aspiration cytology of benign fibrous histiocytoma of bone : A case report. / Bharatnur, Shankaranand Siddappa; Ramesh Naik, Chamarajanagar Nanjanayak; Swethadri, Gumballi Krishnamurthy; Fernandes, Hilda; Shekhar, Jayaprakash Chandra; Marla, Nisha Jayashankar.

In: Acta Cytologica, Vol. 54, No. 1, 01.01.2010, p. 89-91.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fine needle aspiration cytology of benign fibrous histiocytoma of bone

T2 - A case report

AU - Bharatnur, Shankaranand Siddappa

AU - Ramesh Naik, Chamarajanagar Nanjanayak

AU - Swethadri, Gumballi Krishnamurthy

AU - Fernandes, Hilda

AU - Shekhar, Jayaprakash Chandra

AU - Marla, Nisha Jayashankar

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Background: Benign fibrous histiocytoma (BFH) of bone is a very rare tumor, and almost all reported cases were diagnosed after surgical resection by histologic examination. We report a case in which cytologic features of BFH of bone were established preoperatively by fine needle aspiration (FNA). To the best of our knowledge, FNA findings of BFH of bone have not been. previously reported. Case: A 30-year-old man presented with pain in the right knee of 3 days' duration. Radiographs of the distal femur showed a lytic lesion. FNA biopsy followed by cytologic examination revealed highly cellular smears with spindle-shaped cells arranged in sheets; papillary fronds and storiform pattern. These cells had a moderate amount of cytoplasm and round to elongated nuclei with inconspicuous nucleoli. Multinucleate giant cells were occasionally seen. A cytologic diagnosis of Giant cell tumor of bone with a BFH component was rendered. Histology revealed a pure BPH of bone. Conclusion: The current case reveals the cytomorphologic features of BFH of bone. Cytology may permit the preoperative recognition of the lesion, allowing a more sound therapeutic approach.

AB - Background: Benign fibrous histiocytoma (BFH) of bone is a very rare tumor, and almost all reported cases were diagnosed after surgical resection by histologic examination. We report a case in which cytologic features of BFH of bone were established preoperatively by fine needle aspiration (FNA). To the best of our knowledge, FNA findings of BFH of bone have not been. previously reported. Case: A 30-year-old man presented with pain in the right knee of 3 days' duration. Radiographs of the distal femur showed a lytic lesion. FNA biopsy followed by cytologic examination revealed highly cellular smears with spindle-shaped cells arranged in sheets; papillary fronds and storiform pattern. These cells had a moderate amount of cytoplasm and round to elongated nuclei with inconspicuous nucleoli. Multinucleate giant cells were occasionally seen. A cytologic diagnosis of Giant cell tumor of bone with a BFH component was rendered. Histology revealed a pure BPH of bone. Conclusion: The current case reveals the cytomorphologic features of BFH of bone. Cytology may permit the preoperative recognition of the lesion, allowing a more sound therapeutic approach.

UR - http://www.scopus.com/inward/record.url?scp=76549084363&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76549084363&partnerID=8YFLogxK

U2 - 10.1159/000324976

DO - 10.1159/000324976

M3 - Article

AN - SCOPUS:76549084363

VL - 54

SP - 89

EP - 91

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 1

ER -

Bharatnur SS, Ramesh Naik CN, Swethadri GK, Fernandes H, Shekhar JC, Marla NJ. Fine needle aspiration cytology of benign fibrous histiocytoma of bone: A case report. Acta Cytologica. 2010 Jan 1;54(1):89-91. https://doi.org/10.1159/000324976