Glaucoma is the second main cause of irreversible blindness in the globe. Increased intraocular pressure (IOP) is the modifiable risk factor of glaucoma. It is either due to overproduction of aqueous humor or defective drainage system. A simulation model of the human eye with varying IOPs was modeled to quantify the stress exerted in the anterior segment of the eye. A 3D model of the human eye was modeled using COMSOL Multiphysics®. This model comprised of nine distinct components of the eye such as cornea, aqueous humor, lens, ciliary body, zonules, vitreous humor, retina, sclera, and optic nerve. Finite element analysis (FEA) was carried out to study the biomechanical changes on these structures of the eye upon varying IOPs. The von Mises stress and displacement were obtained as the result. Elevated IOP caused increase stress on ciliary body and displacement of lens and cornea. FEM has potential usefulness as a simulation tool in understanding the effect of increased IOP on the anterior segment.