In this work, a 3D urinary bladder was subjected to various pressure loading conditions mimicking the bladder filling volume. The bladder layer consisting of adventitia, detrusor and mucosa layer having different mechanical properties produced different deformation and stresses when subjected to the varying loads. The volume of the bladder changed to 231.34ml which was 128.91% higher than the assumed initial volume of 50ml on application of 18kPa of pressure. The detrusor layer which is thickest of the bladder wall reduced to 1.312mm from 4.4mm, recording a 108% change in its thickness at 18kPa pressure. The maximum von-Mises stress obtained were significantly higher in case of the Mucosa layer when compared to the detrusor and adventia layer. The unique layup of the bladder wall having different properties plays a major role in sustaining adverse pressure gradients and absorbing high stresses.
All Science Journal Classification (ASJC) codes
- Biomedical Engineering