Formulation and evaluation of directly compressible dispersible tablets of panchagni lavana

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Abstract

Formulation of ayurvedic powder preparations into tablets may increase dosage uniformity. Application of direct compression method to ayurvedic preparations can be regarded as a major advance. In the present study, dispersible tablets of panchagni lavana were prepared by direct compression method. Panchagnl lavana was subjected to preformulation studies to test the suitability of direct compression method and appropriate formulations were developed. These formulations were further evaluated for hardness, friability, weight variation, uniformity of dispersion, disintegration test and stability studies. Attempts were made to get minimum possible disintegration time by varying the concentrations of sodium starch glycolate and starch. It was found that, use of mixture of both the disintegrating agents was highly useful in the formulation of dispersible tablets of panchagni lavana.The study further revealed the usefulness of direct compression method to formulate dispersible tablets of ayurvedic preparations.

Original languageEnglish
Pages (from-to)128-131
Number of pages4
JournalIndian Journal of Pharmaceutical Sciences
Volume63
Issue number2
Publication statusPublished - 2001

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Tablets
Hardness
Starch
Powders
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

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abstract = "Formulation of ayurvedic powder preparations into tablets may increase dosage uniformity. Application of direct compression method to ayurvedic preparations can be regarded as a major advance. In the present study, dispersible tablets of panchagni lavana were prepared by direct compression method. Panchagnl lavana was subjected to preformulation studies to test the suitability of direct compression method and appropriate formulations were developed. These formulations were further evaluated for hardness, friability, weight variation, uniformity of dispersion, disintegration test and stability studies. Attempts were made to get minimum possible disintegration time by varying the concentrations of sodium starch glycolate and starch. It was found that, use of mixture of both the disintegrating agents was highly useful in the formulation of dispersible tablets of panchagni lavana.The study further revealed the usefulness of direct compression method to formulate dispersible tablets of ayurvedic preparations.",
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