Formulation and evaluation of methotrexate niosomes

N. Udupa, K. S. Chandraprakash, P. Umadevi, G. K. Pillai

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.

Original languageEnglish
Pages (from-to)1331-1342
Number of pages12
JournalDrug Development and Industrial Pharmacy
Volume19
Issue number11
DOIs
Publication statusPublished - 01-01-1993

Fingerprint

Methotrexate
Liposomes
Sarcoma 180
Pharmacokinetics
Polysorbates
Tumors
Neoplasms
sorbitan monostearate

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Organic Chemistry

Cite this

Udupa, N. ; Chandraprakash, K. S. ; Umadevi, P. ; Pillai, G. K. / Formulation and evaluation of methotrexate niosomes. In: Drug Development and Industrial Pharmacy. 1993 ; Vol. 19, No. 11. pp. 1331-1342.
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Formulation and evaluation of methotrexate niosomes. / Udupa, N.; Chandraprakash, K. S.; Umadevi, P.; Pillai, G. K.

In: Drug Development and Industrial Pharmacy, Vol. 19, No. 11, 01.01.1993, p. 1331-1342.

Research output: Contribution to journalArticle

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