The free radical scavenging potential of the plant Sphaeranthus indicus Linn. was studied by using different antioxidant models of screening. The aqueous extract at 1000 μg/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) (ABTS) observed upto 26.21 % followed by the scavenging of the stable radical 1,1-diphenyl, 2-picryl hydrazyl (DPPH) (24.95 %), superoxide dismutase (17.74 %) and nitric oxide radical (10.63 %) at the same concentration. However, the extract showed only moderate scavenging activity of iron chelation (9.62 %). Total antioxidant capacity of the extract was found to be 127.85 nmol/g ascorbic acid. The findings justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
|Number of pages||9|
|Publication status||Published - 2009|
Prabhu, K. S., Lobo, R., & Shirwaikar, A. (2009). Free radical scavenging activity of aqueous extract of Sphaeranthus indicus (LINN). Pharmacologyonline, 2, 468-476. https://www.scopus.com/inward/record.uri?eid=2-s2.0-70249137269&partnerID=40&md5=f9645f1187fe3d9c7a892fb4d39d4d35