Gamma glutamyl transpeptidase and total cholesterol levels in smokers and congestive cardiac failure patients

Sreekantha, Vinodchandran, M. Amareshwar, S. S. Avinash, Remya, M. V. Kodliwadmath

Research output: Contribution to journalArticle

Abstract

Background and Objectives The level of gamma glutamye transpeptidase (GGTP or GGT) is especifically increased in alcoholic liver diseases with biliary obstruction. There are many other diseases where alterations in the level of GGTP are noted. Hence, the study was aimed to estimate the level of GGTP in smokers and congestive cardiac failure (CCF) patients along with total cholesterol (TC). Material and Methods 35 each clinically diagnosed CCF patients, smokers and normal healthy male subjects were included in the study. GGTP was estimated by enzymatic colorimetric method and total cholesterol by cholesterol oxidase peroxidase method using P-800 chemistry antoanalyser. Statistical analysis was done using ANOVA. Results The GGTP and TC levels were significantly (p<0.001) increased in the both CCF patients and smokers but increase is more significant in CCF patients. Conclusion GGTP can be used as a potential biomarker along with total cholesterol in cardiovascular diseases especially CCF because of their direct relationship with the indication of atherogenesis.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalIndian Journal of Public Health Research and Development
Volume3
Issue number2
Publication statusPublished - 01-04-2012
Externally publishedYes

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gamma-Glutamyltransferase
Heart Failure
Cholesterol
Cholesterol Oxidase
Peptidyl Transferases
Alcoholic Liver Diseases
Peroxidase
Atherosclerosis
Analysis of Variance
Healthy Volunteers
Cardiovascular Diseases
Biomarkers

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

Sreekantha, Vinodchandran, Amareshwar, M., Avinash, S. S., Remya, & Kodliwadmath, M. V. (2012). Gamma glutamyl transpeptidase and total cholesterol levels in smokers and congestive cardiac failure patients. Indian Journal of Public Health Research and Development, 3(2), 165-167.
Sreekantha ; Vinodchandran ; Amareshwar, M. ; Avinash, S. S. ; Remya ; Kodliwadmath, M. V. / Gamma glutamyl transpeptidase and total cholesterol levels in smokers and congestive cardiac failure patients. In: Indian Journal of Public Health Research and Development. 2012 ; Vol. 3, No. 2. pp. 165-167.
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Sreekantha, Vinodchandran, Amareshwar, M, Avinash, SS, Remya & Kodliwadmath, MV 2012, 'Gamma glutamyl transpeptidase and total cholesterol levels in smokers and congestive cardiac failure patients', Indian Journal of Public Health Research and Development, vol. 3, no. 2, pp. 165-167.

Gamma glutamyl transpeptidase and total cholesterol levels in smokers and congestive cardiac failure patients. / Sreekantha; Vinodchandran; Amareshwar, M.; Avinash, S. S.; Remya; Kodliwadmath, M. V.

In: Indian Journal of Public Health Research and Development, Vol. 3, No. 2, 01.04.2012, p. 165-167.

Research output: Contribution to journalArticle

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AU - Kodliwadmath, M. V.

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N2 - Background and Objectives The level of gamma glutamye transpeptidase (GGTP or GGT) is especifically increased in alcoholic liver diseases with biliary obstruction. There are many other diseases where alterations in the level of GGTP are noted. Hence, the study was aimed to estimate the level of GGTP in smokers and congestive cardiac failure (CCF) patients along with total cholesterol (TC). Material and Methods 35 each clinically diagnosed CCF patients, smokers and normal healthy male subjects were included in the study. GGTP was estimated by enzymatic colorimetric method and total cholesterol by cholesterol oxidase peroxidase method using P-800 chemistry antoanalyser. Statistical analysis was done using ANOVA. Results The GGTP and TC levels were significantly (p<0.001) increased in the both CCF patients and smokers but increase is more significant in CCF patients. Conclusion GGTP can be used as a potential biomarker along with total cholesterol in cardiovascular diseases especially CCF because of their direct relationship with the indication of atherogenesis.

AB - Background and Objectives The level of gamma glutamye transpeptidase (GGTP or GGT) is especifically increased in alcoholic liver diseases with biliary obstruction. There are many other diseases where alterations in the level of GGTP are noted. Hence, the study was aimed to estimate the level of GGTP in smokers and congestive cardiac failure (CCF) patients along with total cholesterol (TC). Material and Methods 35 each clinically diagnosed CCF patients, smokers and normal healthy male subjects were included in the study. GGTP was estimated by enzymatic colorimetric method and total cholesterol by cholesterol oxidase peroxidase method using P-800 chemistry antoanalyser. Statistical analysis was done using ANOVA. Results The GGTP and TC levels were significantly (p<0.001) increased in the both CCF patients and smokers but increase is more significant in CCF patients. Conclusion GGTP can be used as a potential biomarker along with total cholesterol in cardiovascular diseases especially CCF because of their direct relationship with the indication of atherogenesis.

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