Gastric mucormycosis masquerading as malignancy in an immunocompetent host

Baise C. Pruthvi, C. K.Anuradha Rao, Sundar Rupashree, Suvarna Deepak, Shanbhogue Vikram, Belle Jayaprakash, Neeleshwar R. Rau, Lakshmi Rao

Research output: Contribution to journalArticle

Abstract

Mucormycosis is an uncommon, fatal, fungal infection occurring more often in immunocompromised patients. Gastrointestinal mucormycosis is rare, and found primarily in patients with extreme malnutrition. This is a case report of a 76-year-old, well-nourished immunocompetent, non-diabetic male patient, who presented with urinary tract infection, for whom broad-spectrum antibiotics were administered. Reducing haemoglobin levels and occult blood positivity in stools prompted a gastroscopy, which showed a large ulcerated growth in the body of the stomach, suspicious of malignancy. Subsequent biopsy and histopathological examination revealed gastric mucormycosis. The patient was administered intravenous amphotericin B for 6 weeks. Complete recovery followed, as evidenced by a healed ulcer on gastroscopy and no fungal elements on biopsy. Although gastrointestinal mucormycosis has been reported with fatal outcome, our patient had complete recovery with only medical management and no surgical intervention, highlighting the importance of early diagnosis.

Original languageEnglish
Pages (from-to)227-229
Number of pages3
JournalArab Journal of Gastroenterology
Volume11
Issue number4
DOIs
Publication statusPublished - 01-12-2010

Fingerprint

Mucormycosis
Stomach
Gastroscopy
Neoplasms
Biopsy
Occult Blood
Fatal Outcome
Mycoses
Immunocompromised Host
Amphotericin B
Urinary Tract Infections
Malnutrition
Ulcer
Early Diagnosis
Hemoglobins
Anti-Bacterial Agents
Growth

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Pruthvi, B. C., Rao, C. K. A., Rupashree, S., Deepak, S., Vikram, S., Jayaprakash, B., ... Rao, L. (2010). Gastric mucormycosis masquerading as malignancy in an immunocompetent host. Arab Journal of Gastroenterology, 11(4), 227-229. https://doi.org/10.1016/j.ajg.2010.09.006
Pruthvi, Baise C. ; Rao, C. K.Anuradha ; Rupashree, Sundar ; Deepak, Suvarna ; Vikram, Shanbhogue ; Jayaprakash, Belle ; Rau, Neeleshwar R. ; Rao, Lakshmi. / Gastric mucormycosis masquerading as malignancy in an immunocompetent host. In: Arab Journal of Gastroenterology. 2010 ; Vol. 11, No. 4. pp. 227-229.
@article{ddb3d7ef16674a5db2c7f4e20cbcfa88,
title = "Gastric mucormycosis masquerading as malignancy in an immunocompetent host",
abstract = "Mucormycosis is an uncommon, fatal, fungal infection occurring more often in immunocompromised patients. Gastrointestinal mucormycosis is rare, and found primarily in patients with extreme malnutrition. This is a case report of a 76-year-old, well-nourished immunocompetent, non-diabetic male patient, who presented with urinary tract infection, for whom broad-spectrum antibiotics were administered. Reducing haemoglobin levels and occult blood positivity in stools prompted a gastroscopy, which showed a large ulcerated growth in the body of the stomach, suspicious of malignancy. Subsequent biopsy and histopathological examination revealed gastric mucormycosis. The patient was administered intravenous amphotericin B for 6 weeks. Complete recovery followed, as evidenced by a healed ulcer on gastroscopy and no fungal elements on biopsy. Although gastrointestinal mucormycosis has been reported with fatal outcome, our patient had complete recovery with only medical management and no surgical intervention, highlighting the importance of early diagnosis.",
author = "Pruthvi, {Baise C.} and Rao, {C. K.Anuradha} and Sundar Rupashree and Suvarna Deepak and Shanbhogue Vikram and Belle Jayaprakash and Rau, {Neeleshwar R.} and Lakshmi Rao",
year = "2010",
month = "12",
day = "1",
doi = "10.1016/j.ajg.2010.09.006",
language = "English",
volume = "11",
pages = "227--229",
journal = "Arab Journal of Gastroenterology",
issn = "1687-1979",
publisher = "Elsevier BV",
number = "4",

}

Pruthvi, BC, Rao, CKA, Rupashree, S, Deepak, S, Vikram, S, Jayaprakash, B, Rau, NR & Rao, L 2010, 'Gastric mucormycosis masquerading as malignancy in an immunocompetent host', Arab Journal of Gastroenterology, vol. 11, no. 4, pp. 227-229. https://doi.org/10.1016/j.ajg.2010.09.006

Gastric mucormycosis masquerading as malignancy in an immunocompetent host. / Pruthvi, Baise C.; Rao, C. K.Anuradha; Rupashree, Sundar; Deepak, Suvarna; Vikram, Shanbhogue; Jayaprakash, Belle; Rau, Neeleshwar R.; Rao, Lakshmi.

In: Arab Journal of Gastroenterology, Vol. 11, No. 4, 01.12.2010, p. 227-229.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Gastric mucormycosis masquerading as malignancy in an immunocompetent host

AU - Pruthvi, Baise C.

AU - Rao, C. K.Anuradha

AU - Rupashree, Sundar

AU - Deepak, Suvarna

AU - Vikram, Shanbhogue

AU - Jayaprakash, Belle

AU - Rau, Neeleshwar R.

AU - Rao, Lakshmi

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Mucormycosis is an uncommon, fatal, fungal infection occurring more often in immunocompromised patients. Gastrointestinal mucormycosis is rare, and found primarily in patients with extreme malnutrition. This is a case report of a 76-year-old, well-nourished immunocompetent, non-diabetic male patient, who presented with urinary tract infection, for whom broad-spectrum antibiotics were administered. Reducing haemoglobin levels and occult blood positivity in stools prompted a gastroscopy, which showed a large ulcerated growth in the body of the stomach, suspicious of malignancy. Subsequent biopsy and histopathological examination revealed gastric mucormycosis. The patient was administered intravenous amphotericin B for 6 weeks. Complete recovery followed, as evidenced by a healed ulcer on gastroscopy and no fungal elements on biopsy. Although gastrointestinal mucormycosis has been reported with fatal outcome, our patient had complete recovery with only medical management and no surgical intervention, highlighting the importance of early diagnosis.

AB - Mucormycosis is an uncommon, fatal, fungal infection occurring more often in immunocompromised patients. Gastrointestinal mucormycosis is rare, and found primarily in patients with extreme malnutrition. This is a case report of a 76-year-old, well-nourished immunocompetent, non-diabetic male patient, who presented with urinary tract infection, for whom broad-spectrum antibiotics were administered. Reducing haemoglobin levels and occult blood positivity in stools prompted a gastroscopy, which showed a large ulcerated growth in the body of the stomach, suspicious of malignancy. Subsequent biopsy and histopathological examination revealed gastric mucormycosis. The patient was administered intravenous amphotericin B for 6 weeks. Complete recovery followed, as evidenced by a healed ulcer on gastroscopy and no fungal elements on biopsy. Although gastrointestinal mucormycosis has been reported with fatal outcome, our patient had complete recovery with only medical management and no surgical intervention, highlighting the importance of early diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=78649691244&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649691244&partnerID=8YFLogxK

U2 - 10.1016/j.ajg.2010.09.006

DO - 10.1016/j.ajg.2010.09.006

M3 - Article

AN - SCOPUS:78649691244

VL - 11

SP - 227

EP - 229

JO - Arab Journal of Gastroenterology

JF - Arab Journal of Gastroenterology

SN - 1687-1979

IS - 4

ER -

Pruthvi BC, Rao CKA, Rupashree S, Deepak S, Vikram S, Jayaprakash B et al. Gastric mucormycosis masquerading as malignancy in an immunocompetent host. Arab Journal of Gastroenterology. 2010 Dec 1;11(4):227-229. https://doi.org/10.1016/j.ajg.2010.09.006