Giant-cell fibroma: Understanding the nature of the melanin-laden cells

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Abstract

Giant-cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant-cell fibroma with stroma strewn with brown pigment-laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Various mechanisms that explain the presence of melanin granules in reactive lesions of giant-cell fibroma is discussed in the present report.

Original languageEnglish
Pages (from-to)429-433
Number of pages5
JournalJournal of Oral and Maxillofacial Pathology
Volume21
Issue number3
DOIs
Publication statusPublished - 01-09-2017

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All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Otorhinolaryngology

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