Abstract
To report oral topiramate-induced glaucoma and to asses its severity and preventability. A 40-year-old manpresented with watering, redness, pain, and diminution of vision of both eyes, one week after initiation of oral topiramate 100 mg/day for alcohol de-addiction. On examination, both eyes showed conjunctival chemosis, corneal edema, shallow anterior chamber, and intraocular pressure 48 and 46 mm Hg. The symptoms and clinical findings resolved completely upon discontinuation of topiramate and administration of antiglaucoma drugs. Topiramate-induced angle-closure glaucoma and other ocular side effects are reversible if the diagnosis is made early and the drug is discontinued in time. Hence, clinician awareness is an important aspect of preventability of this adverse event.
| Original language | English |
|---|---|
| Pages (from-to) | 163-165 |
| Number of pages | 3 |
| Journal | Indian Journal of Psychiatry |
| Volume | 53 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 01-04-2011 |
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All Science Journal Classification (ASJC) codes
- Psychiatry and Mental health
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Glaucoma : Adverse event on use of topiramate in alcohol de-addiction. / Pai, Keshava; Rajashekaran, Pooja.
In: Indian Journal of Psychiatry, Vol. 53, No. 2, 01.04.2011, p. 163-165.Research output: Contribution to journal › Article
TY - JOUR
T1 - Glaucoma
T2 - Adverse event on use of topiramate in alcohol de-addiction
AU - Pai, Keshava
AU - Rajashekaran, Pooja
PY - 2011/4/1
Y1 - 2011/4/1
N2 - To report oral topiramate-induced glaucoma and to asses its severity and preventability. A 40-year-old manpresented with watering, redness, pain, and diminution of vision of both eyes, one week after initiation of oral topiramate 100 mg/day for alcohol de-addiction. On examination, both eyes showed conjunctival chemosis, corneal edema, shallow anterior chamber, and intraocular pressure 48 and 46 mm Hg. The symptoms and clinical findings resolved completely upon discontinuation of topiramate and administration of antiglaucoma drugs. Topiramate-induced angle-closure glaucoma and other ocular side effects are reversible if the diagnosis is made early and the drug is discontinued in time. Hence, clinician awareness is an important aspect of preventability of this adverse event.
AB - To report oral topiramate-induced glaucoma and to asses its severity and preventability. A 40-year-old manpresented with watering, redness, pain, and diminution of vision of both eyes, one week after initiation of oral topiramate 100 mg/day for alcohol de-addiction. On examination, both eyes showed conjunctival chemosis, corneal edema, shallow anterior chamber, and intraocular pressure 48 and 46 mm Hg. The symptoms and clinical findings resolved completely upon discontinuation of topiramate and administration of antiglaucoma drugs. Topiramate-induced angle-closure glaucoma and other ocular side effects are reversible if the diagnosis is made early and the drug is discontinued in time. Hence, clinician awareness is an important aspect of preventability of this adverse event.
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UR - http://www.scopus.com/inward/citedby.url?scp=79960254652&partnerID=8YFLogxK
U2 - 10.4103/0019-5545.82552
DO - 10.4103/0019-5545.82552
M3 - Article
VL - 53
SP - 163
EP - 165
JO - Indian Journal of Psychiatry
JF - Indian Journal of Psychiatry
SN - 0019-5545
IS - 2
ER -