Glaucoma in aphakia and pseudophakia in the Chennai Glaucoma Study

H. Arvind, R. George, P. Raju, S. V. Ramesh, M. Baskaran, P. G. Paul, C. McCarty, Lingam Vijaya

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Abstract

Aim: To determine the prevalence of glaucoma among aphakes and pseudophakes in a rural population of southern India. Methods: 3924 subjects aged 40 years or above underwent complete ophthalmic examination. Glaucoma in aphakia/pseudophakia was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria in aphakic/pseudophakic people. Results: 54 subjects (37 aphakes, 17 pseudophakes) (1.38% of 3924 subjects, 11.2% of 482 aphakes/pseudophakes) had glaucoma in aphakia/pseudophakia. Aphakia, age, intraocular pressure (IOP), pseudoexfoliation, and peripheral anterior synechiae greater than or equal to 180 degrees of the angle were risk factors for glaucoma on univariate analysts. On multivariate analysis, IOP and aphakia were independent risk factors for glaucoma. 39 people (72.22%) with glaucoma had normal IOP at presentation. None of the people with glaucoma were aware of the disease. Blindness in one or both eyes was seen in 12 subjects (10 unilateral and two bilateral) - that is, 22.22% of people with glaucoma in aphakia/pseudophakia. Conclusions: Glaucoma is an important cause of ocular morbidity among aphakes and pseudophakes in this rural population of south India. This glaucoma, responsible for unilateral or bilateral blindness in 22.2% of those affected, was entirely undetected in this study population.

Original languageEnglish
Pages (from-to)699-703
Number of pages5
JournalBritish Journal of Ophthalmology
Volume89
Issue number6
DOIs
Publication statusPublished - 01-06-2005

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Pseudophakia
Aphakia
Glaucoma
Intraocular Pressure
Rural Population
Blindness
India
Ophthalmology
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Arvind, H. ; George, R. ; Raju, P. ; Ramesh, S. V. ; Baskaran, M. ; Paul, P. G. ; McCarty, C. ; Vijaya, Lingam. / Glaucoma in aphakia and pseudophakia in the Chennai Glaucoma Study. In: British Journal of Ophthalmology. 2005 ; Vol. 89, No. 6. pp. 699-703.
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abstract = "Aim: To determine the prevalence of glaucoma among aphakes and pseudophakes in a rural population of southern India. Methods: 3924 subjects aged 40 years or above underwent complete ophthalmic examination. Glaucoma in aphakia/pseudophakia was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria in aphakic/pseudophakic people. Results: 54 subjects (37 aphakes, 17 pseudophakes) (1.38{\%} of 3924 subjects, 11.2{\%} of 482 aphakes/pseudophakes) had glaucoma in aphakia/pseudophakia. Aphakia, age, intraocular pressure (IOP), pseudoexfoliation, and peripheral anterior synechiae greater than or equal to 180 degrees of the angle were risk factors for glaucoma on univariate analysts. On multivariate analysis, IOP and aphakia were independent risk factors for glaucoma. 39 people (72.22{\%}) with glaucoma had normal IOP at presentation. None of the people with glaucoma were aware of the disease. Blindness in one or both eyes was seen in 12 subjects (10 unilateral and two bilateral) - that is, 22.22{\%} of people with glaucoma in aphakia/pseudophakia. Conclusions: Glaucoma is an important cause of ocular morbidity among aphakes and pseudophakes in this rural population of south India. This glaucoma, responsible for unilateral or bilateral blindness in 22.2{\%} of those affected, was entirely undetected in this study population.",
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Arvind, H, George, R, Raju, P, Ramesh, SV, Baskaran, M, Paul, PG, McCarty, C & Vijaya, L 2005, 'Glaucoma in aphakia and pseudophakia in the Chennai Glaucoma Study', British Journal of Ophthalmology, vol. 89, no. 6, pp. 699-703. https://doi.org/10.1136/bjo.2004.056234

Glaucoma in aphakia and pseudophakia in the Chennai Glaucoma Study. / Arvind, H.; George, R.; Raju, P.; Ramesh, S. V.; Baskaran, M.; Paul, P. G.; McCarty, C.; Vijaya, Lingam.

In: British Journal of Ophthalmology, Vol. 89, No. 6, 01.06.2005, p. 699-703.

Research output: Contribution to journalArticle

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AU - George, R.

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N2 - Aim: To determine the prevalence of glaucoma among aphakes and pseudophakes in a rural population of southern India. Methods: 3924 subjects aged 40 years or above underwent complete ophthalmic examination. Glaucoma in aphakia/pseudophakia was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria in aphakic/pseudophakic people. Results: 54 subjects (37 aphakes, 17 pseudophakes) (1.38% of 3924 subjects, 11.2% of 482 aphakes/pseudophakes) had glaucoma in aphakia/pseudophakia. Aphakia, age, intraocular pressure (IOP), pseudoexfoliation, and peripheral anterior synechiae greater than or equal to 180 degrees of the angle were risk factors for glaucoma on univariate analysts. On multivariate analysis, IOP and aphakia were independent risk factors for glaucoma. 39 people (72.22%) with glaucoma had normal IOP at presentation. None of the people with glaucoma were aware of the disease. Blindness in one or both eyes was seen in 12 subjects (10 unilateral and two bilateral) - that is, 22.22% of people with glaucoma in aphakia/pseudophakia. Conclusions: Glaucoma is an important cause of ocular morbidity among aphakes and pseudophakes in this rural population of south India. This glaucoma, responsible for unilateral or bilateral blindness in 22.2% of those affected, was entirely undetected in this study population.

AB - Aim: To determine the prevalence of glaucoma among aphakes and pseudophakes in a rural population of southern India. Methods: 3924 subjects aged 40 years or above underwent complete ophthalmic examination. Glaucoma in aphakia/pseudophakia was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria in aphakic/pseudophakic people. Results: 54 subjects (37 aphakes, 17 pseudophakes) (1.38% of 3924 subjects, 11.2% of 482 aphakes/pseudophakes) had glaucoma in aphakia/pseudophakia. Aphakia, age, intraocular pressure (IOP), pseudoexfoliation, and peripheral anterior synechiae greater than or equal to 180 degrees of the angle were risk factors for glaucoma on univariate analysts. On multivariate analysis, IOP and aphakia were independent risk factors for glaucoma. 39 people (72.22%) with glaucoma had normal IOP at presentation. None of the people with glaucoma were aware of the disease. Blindness in one or both eyes was seen in 12 subjects (10 unilateral and two bilateral) - that is, 22.22% of people with glaucoma in aphakia/pseudophakia. Conclusions: Glaucoma is an important cause of ocular morbidity among aphakes and pseudophakes in this rural population of south India. This glaucoma, responsible for unilateral or bilateral blindness in 22.2% of those affected, was entirely undetected in this study population.

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