Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis

Subramanian Kumudhini, Raghavendra Rao, Gauri Salgaonkar, Sricharith Shetty, Sathish Pai

Research output: Contribution to journalArticle

Abstract

Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

Original languageEnglish
Number of pages1
JournalIndian Journal of Dermatology
Volume61
Issue number5
DOIs
Publication statusPublished - 01-09-2016

Fingerprint

Cutaneous Mastocytosis
Basement Membrane
Immunoglobulin M
Mast Cells
Skin
Direct Fluorescent Antibody Technique
Blister
Fluorescence Microscopy
Eosinophils
Neutrophils
Biopsy

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis. / Kumudhini, Subramanian; Rao, Raghavendra; Salgaonkar, Gauri; Shetty, Sricharith; Pai, Sathish.

In: Indian Journal of Dermatology, Vol. 61, No. 5, 01.09.2016.

Research output: Contribution to journalArticle

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AU - Kumudhini, Subramanian

AU - Rao, Raghavendra

AU - Salgaonkar, Gauri

AU - Shetty, Sricharith

AU - Pai, Sathish

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