Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis

Subramanian Kumudhini, Raghavendra Rao, Gauri Salgaonkar, Sricharith Shetty, Sathish Pai

Research output: Contribution to journalArticle


Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

Original languageEnglish
Number of pages1
JournalIndian Journal of Dermatology
Issue number5
Publication statusPublished - 01-09-2016


All Science Journal Classification (ASJC) codes

  • Dermatology

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