TY - JOUR
T1 - Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis
AU - Kumudhini, Subramanian
AU - Rao, Raghavendra
AU - Salgaonkar, Gauri
AU - Shetty, Sricharith
AU - Pai, Sathish
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.
AB - Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.
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U2 - 10.4103/0019-5154.190134
DO - 10.4103/0019-5154.190134
M3 - Article
AN - SCOPUS:84987803024
SN - 0019-5154
VL - 61
JO - Indian Journal of Dermatology
JF - Indian Journal of Dermatology
IS - 5
ER -