Abstract

Granuloma multiforme (GM) is a chronic granulomatous skin condition which is clinically characterised by annular lesions mainly over sun-exposed areas and histologically by focal necrobiosis and histiocytic granulomas. Its significance lies in the fact that it can clinically resemble tuberculoid leprosy and hence it can be missed. Here, we report a case of GM from India in a 55-year-old female agriculturist, with multiple asymptomatic large annular rings of papules over the photo-distributed areas. Histopathology helps in confirming the diagnosis and in differentiating it from similar clinical and histologic mimics such as granuloma annulare, tuberculoid leprosy, interstitial granulomatous dermatitis or annular sarcoid. Though a high degree of suspicion is needed to diagnose GM, it should be considered as a differential for various annular conditions.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalTropical Doctor
Volume49
Issue number1
DOIs
Publication statusPublished - 01-01-2019

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Leprosy
Granuloma
Tuberculoid Leprosy
Necrobiotic Disorders
Granuloma Annulare
Solar System
Dermatitis
India
Skin

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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abstract = "Granuloma multiforme (GM) is a chronic granulomatous skin condition which is clinically characterised by annular lesions mainly over sun-exposed areas and histologically by focal necrobiosis and histiocytic granulomas. Its significance lies in the fact that it can clinically resemble tuberculoid leprosy and hence it can be missed. Here, we report a case of GM from India in a 55-year-old female agriculturist, with multiple asymptomatic large annular rings of papules over the photo-distributed areas. Histopathology helps in confirming the diagnosis and in differentiating it from similar clinical and histologic mimics such as granuloma annulare, tuberculoid leprosy, interstitial granulomatous dermatitis or annular sarcoid. Though a high degree of suspicion is needed to diagnose GM, it should be considered as a differential for various annular conditions.",
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Granuloma multiforme : an uncommon differential for leprosy. / Bhatia, Shibani; Shenoi, Shrutakirthi D.; Pai, Kanthilatha; Srilatha, P. S.

In: Tropical Doctor, Vol. 49, No. 1, 01.01.2019, p. 55-58.

Research output: Contribution to journalArticle

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