Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India

Chandana Sai Hari Alladi, Anitha Jagadesh, Suresha G. Prabhu, Govindakarnavar Arunkumar

Research output: Contribution to journalArticle

Abstract

Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.

Original languageEnglish
Pages (from-to)230-233
Number of pages4
JournalViral Immunology
Volume32
Issue number5
DOIs
Publication statusPublished - 01-06-2019

All Science Journal Classification (ASJC) codes

  • Immunology
  • Molecular Medicine
  • Virology

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