TY - JOUR
T1 - Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection
T2 - A Cross-Sectional Study from Thirthahalli, Karnataka, India
AU - Alladi, Chandana Sai Hari
AU - Jagadesh, Anitha
AU - Prabhu, Suresha G.
AU - Arunkumar, Govindakarnavar
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.
AB - Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.
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U2 - 10.1089/vim.2019.0010
DO - 10.1089/vim.2019.0010
M3 - Article
C2 - 31070522
AN - SCOPUS:85066990039
SN - 0882-8245
VL - 32
SP - 230
EP - 233
JO - Viral Immunology
JF - Viral Immunology
IS - 5
ER -