Hematocrit as a simple method to predict and manage ovarian hyperstimulation syndrome in assisted reproduction

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The aim was to analyze the hematocrit levels in cases of ovarian hyperstimulation syndrome (OHSS), syndrome occurring during in-vitro fertilization (IVF), and study its role as a prognostic indicator. Subjects and Methods: Two years data of 66 women at high risk for developing OHSS was analyzed. Twenty-seven women who developed OHSS were further analyzed based on their hematocrit levels on the day of oocyte pick-up (OPU) and the day of embryo transfer (ET) to see if there was a prognostic trend. Results: Of the total 225 IVF cases, 66 were deemed high risk for developing OHSS. Twenty-seven of these developed OHSS (40.9%). Of these 27, 21 (77.8%) had a hematocrit >35% on the day of OPU. The mean hematocrit in women developing OHSS on the day of OPU was 37.39% (standard deviation [SD] 2.66) as against 35.97% (2.80) in those not developing OHSS. This difference was statistically significant (P = 0.043). On the day of ET, 23/27 (85.8%) who developed OHSS had a hematocrit of >35%. The mean hematocrit was 39.29% (SD 3.85) in those who developed OHSS as against 34.7% (2.88) in those who did not. This difference (4.85) was statistically significant (P < 0.001). Conclusions: Women undergoing IVF were at a higher risk of developing OHSS when their hematocrit on the day of OPU and ET was >35%. Those who required cancellation of ET had a hematocrit of >35% on the day of ET or showed a significant increase of 3% from OPU to ET.

Original languageEnglish
Pages (from-to)93-97
Number of pages5
JournalJournal of Human Reproductive Sciences
Volume8
Issue number2
DOIs
Publication statusPublished - 01-01-2015

Fingerprint

Ovarian Hyperstimulation Syndrome
Hematocrit
Reproduction
Embryo Transfer
Oocytes
Fertilization in Vitro

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine

Cite this

@article{38f8ce02519e4f44bb82bf54cbfa0e10,
title = "Hematocrit as a simple method to predict and manage ovarian hyperstimulation syndrome in assisted reproduction",
abstract = "The aim was to analyze the hematocrit levels in cases of ovarian hyperstimulation syndrome (OHSS), syndrome occurring during in-vitro fertilization (IVF), and study its role as a prognostic indicator. Subjects and Methods: Two years data of 66 women at high risk for developing OHSS was analyzed. Twenty-seven women who developed OHSS were further analyzed based on their hematocrit levels on the day of oocyte pick-up (OPU) and the day of embryo transfer (ET) to see if there was a prognostic trend. Results: Of the total 225 IVF cases, 66 were deemed high risk for developing OHSS. Twenty-seven of these developed OHSS (40.9{\%}). Of these 27, 21 (77.8{\%}) had a hematocrit >35{\%} on the day of OPU. The mean hematocrit in women developing OHSS on the day of OPU was 37.39{\%} (standard deviation [SD] 2.66) as against 35.97{\%} (2.80) in those not developing OHSS. This difference was statistically significant (P = 0.043). On the day of ET, 23/27 (85.8{\%}) who developed OHSS had a hematocrit of >35{\%}. The mean hematocrit was 39.29{\%} (SD 3.85) in those who developed OHSS as against 34.7{\%} (2.88) in those who did not. This difference (4.85) was statistically significant (P < 0.001). Conclusions: Women undergoing IVF were at a higher risk of developing OHSS when their hematocrit on the day of OPU and ET was >35{\%}. Those who required cancellation of ET had a hematocrit of >35{\%} on the day of ET or showed a significant increase of 3{\%} from OPU to ET.",
author = "Taswin Kaur and Praveena Pai and Pratap Kumar",
year = "2015",
month = "1",
day = "1",
doi = "10.4103/0974-1208.158616",
language = "English",
volume = "8",
pages = "93--97",
journal = "Journal of Human Reproductive Sciences",
issn = "0974-1208",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "2",

}

TY - JOUR

T1 - Hematocrit as a simple method to predict and manage ovarian hyperstimulation syndrome in assisted reproduction

AU - Kaur, Taswin

AU - Pai, Praveena

AU - Kumar, Pratap

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The aim was to analyze the hematocrit levels in cases of ovarian hyperstimulation syndrome (OHSS), syndrome occurring during in-vitro fertilization (IVF), and study its role as a prognostic indicator. Subjects and Methods: Two years data of 66 women at high risk for developing OHSS was analyzed. Twenty-seven women who developed OHSS were further analyzed based on their hematocrit levels on the day of oocyte pick-up (OPU) and the day of embryo transfer (ET) to see if there was a prognostic trend. Results: Of the total 225 IVF cases, 66 were deemed high risk for developing OHSS. Twenty-seven of these developed OHSS (40.9%). Of these 27, 21 (77.8%) had a hematocrit >35% on the day of OPU. The mean hematocrit in women developing OHSS on the day of OPU was 37.39% (standard deviation [SD] 2.66) as against 35.97% (2.80) in those not developing OHSS. This difference was statistically significant (P = 0.043). On the day of ET, 23/27 (85.8%) who developed OHSS had a hematocrit of >35%. The mean hematocrit was 39.29% (SD 3.85) in those who developed OHSS as against 34.7% (2.88) in those who did not. This difference (4.85) was statistically significant (P < 0.001). Conclusions: Women undergoing IVF were at a higher risk of developing OHSS when their hematocrit on the day of OPU and ET was >35%. Those who required cancellation of ET had a hematocrit of >35% on the day of ET or showed a significant increase of 3% from OPU to ET.

AB - The aim was to analyze the hematocrit levels in cases of ovarian hyperstimulation syndrome (OHSS), syndrome occurring during in-vitro fertilization (IVF), and study its role as a prognostic indicator. Subjects and Methods: Two years data of 66 women at high risk for developing OHSS was analyzed. Twenty-seven women who developed OHSS were further analyzed based on their hematocrit levels on the day of oocyte pick-up (OPU) and the day of embryo transfer (ET) to see if there was a prognostic trend. Results: Of the total 225 IVF cases, 66 were deemed high risk for developing OHSS. Twenty-seven of these developed OHSS (40.9%). Of these 27, 21 (77.8%) had a hematocrit >35% on the day of OPU. The mean hematocrit in women developing OHSS on the day of OPU was 37.39% (standard deviation [SD] 2.66) as against 35.97% (2.80) in those not developing OHSS. This difference was statistically significant (P = 0.043). On the day of ET, 23/27 (85.8%) who developed OHSS had a hematocrit of >35%. The mean hematocrit was 39.29% (SD 3.85) in those who developed OHSS as against 34.7% (2.88) in those who did not. This difference (4.85) was statistically significant (P < 0.001). Conclusions: Women undergoing IVF were at a higher risk of developing OHSS when their hematocrit on the day of OPU and ET was >35%. Those who required cancellation of ET had a hematocrit of >35% on the day of ET or showed a significant increase of 3% from OPU to ET.

UR - http://www.scopus.com/inward/record.url?scp=84933526073&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84933526073&partnerID=8YFLogxK

U2 - 10.4103/0974-1208.158616

DO - 10.4103/0974-1208.158616

M3 - Article

VL - 8

SP - 93

EP - 97

JO - Journal of Human Reproductive Sciences

JF - Journal of Human Reproductive Sciences

SN - 0974-1208

IS - 2

ER -