Henoch-Schonlein purpura

An update

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Henoch-Schonlein purpura (HSP), the commonest childhood vasculitis, is characterised by non-thrombocytopaenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. The peak incidence is between the ages of 4 years and 8 years with a male preponderance. Though the diagnosis is usually clinical, a tissue biopsy revealing leucocytoclastic vasculitis is helpful when the presentation is atypical. Renal involvement in the form of an immune complex glomerulonephritis is the most serious long-term complication. The aetiopathogenesis, classification, clinical features, relevant Indian data, and a stepwise management approach with corticosteroids and immunosuppressive agents per the renal histology are discussed.

Original languageEnglish
Pages (from-to)92-98
Number of pages7
JournalIndian Journal of Rheumatology
Volume7
Issue number1 SUPPL.
DOIs
Publication statusPublished - 01-01-2012

Fingerprint

Schoenlein-Henoch Purpura
Kidney
Purpura
Arthralgia
Immunosuppressive Agents
Glomerulonephritis
Vasculitis
Antigen-Antibody Complex
Arthritis
Histology
Adrenal Cortex Hormones
Biopsy
Incidence

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

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title = "Henoch-Schonlein purpura: An update",
abstract = "Henoch-Schonlein purpura (HSP), the commonest childhood vasculitis, is characterised by non-thrombocytopaenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. The peak incidence is between the ages of 4 years and 8 years with a male preponderance. Though the diagnosis is usually clinical, a tissue biopsy revealing leucocytoclastic vasculitis is helpful when the presentation is atypical. Renal involvement in the form of an immune complex glomerulonephritis is the most serious long-term complication. The aetiopathogenesis, classification, clinical features, relevant Indian data, and a stepwise management approach with corticosteroids and immunosuppressive agents per the renal histology are discussed.",
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Henoch-Schonlein purpura : An update. / Kamath, Nutan; Rao, Suchetha.

In: Indian Journal of Rheumatology, Vol. 7, No. 1 SUPPL., 01.01.2012, p. 92-98.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Henoch-Schonlein purpura

T2 - An update

AU - Kamath, Nutan

AU - Rao, Suchetha

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AB - Henoch-Schonlein purpura (HSP), the commonest childhood vasculitis, is characterised by non-thrombocytopaenic palpable purpura, arthritis or arthralgias, gastrointestinal and renal involvement. The peak incidence is between the ages of 4 years and 8 years with a male preponderance. Though the diagnosis is usually clinical, a tissue biopsy revealing leucocytoclastic vasculitis is helpful when the presentation is atypical. Renal involvement in the form of an immune complex glomerulonephritis is the most serious long-term complication. The aetiopathogenesis, classification, clinical features, relevant Indian data, and a stepwise management approach with corticosteroids and immunosuppressive agents per the renal histology are discussed.

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