Highly sensitive C-reactive protein in metabolic syndrome

Sudha Vidyasagar, U. K. Abdul Razak, C. K. Prashanth, D. Muralidhar Varma, K. L. Bairy

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Metabolic syndrome is known to predispose to atherosclerosis. C-reactive protein, a marker of systemic inflammation is significantly associated with the atherosclerotic process. Methods: We prospectively studied the relationship between high-sensitivity C-reactive protein (hs-CRP) with various components of metabolic syndrome in 91 patients with metabolic syndrome at our tertiary care centre in South India. Results: The mean age of patients was 57.5 ± 9.8 years; there were 67 (73.6%) males. On univariate analysis, hs-CRP was found to be significantly increased in patients with diabetes mellitus (p < 0.021) and those with abnormal waist circumference (p<0.003). There was no significant association between hs-CRP and high triglycerides, hypertension, and reduced high density lipoprotein cholesterol. Further, hs-CRP increased significantly with increasing number of components of metabolic syndrome (p< 0.008). Conclusions: Measurement of hs-CRP can be used as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
JournalJournal, Indian Academy of Clinical Medicine
Volume14
Issue number3-4
Publication statusPublished - 16-10-2013

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C-Reactive Protein
Inflammation
Waist Circumference
Tertiary Care Centers
HDL Cholesterol
India
Atherosclerosis
Diabetes Mellitus
Triglycerides
Biomarkers
Hypertension

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Vidyasagar, S., Abdul Razak, U. K., Prashanth, C. K., Muralidhar Varma, D., & Bairy, K. L. (2013). Highly sensitive C-reactive protein in metabolic syndrome. Journal, Indian Academy of Clinical Medicine, 14(3-4), 230-234.
Vidyasagar, Sudha ; Abdul Razak, U. K. ; Prashanth, C. K. ; Muralidhar Varma, D. ; Bairy, K. L. / Highly sensitive C-reactive protein in metabolic syndrome. In: Journal, Indian Academy of Clinical Medicine. 2013 ; Vol. 14, No. 3-4. pp. 230-234.
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Vidyasagar, S, Abdul Razak, UK, Prashanth, CK, Muralidhar Varma, D & Bairy, KL 2013, 'Highly sensitive C-reactive protein in metabolic syndrome', Journal, Indian Academy of Clinical Medicine, vol. 14, no. 3-4, pp. 230-234.

Highly sensitive C-reactive protein in metabolic syndrome. / Vidyasagar, Sudha; Abdul Razak, U. K.; Prashanth, C. K.; Muralidhar Varma, D.; Bairy, K. L.

In: Journal, Indian Academy of Clinical Medicine, Vol. 14, No. 3-4, 16.10.2013, p. 230-234.

Research output: Contribution to journalArticle

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Vidyasagar S, Abdul Razak UK, Prashanth CK, Muralidhar Varma D, Bairy KL. Highly sensitive C-reactive protein in metabolic syndrome. Journal, Indian Academy of Clinical Medicine. 2013 Oct 16;14(3-4):230-234.