Hot and cold

Coexistent Graves' disease and Hashimoto's thyroiditis in a patient with Schmidt's syndrome

Sowjanya Dasari, Kushal Naha, Manjunath Hande, Ganapathiraman Vivek

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 37-year-old housewife presented with generalised fatigue, palpitations and weight loss over the past 3 months. Physical examination revealed signs of hyperthyroidism. Thyroid function tests confirmed the presence of thyrotoxicosis. Pertechnetate radionuclide imaging of the thyroid showed diffusely increased radiotracer uptake consistent with Graves' disease and a cold nodule in the right lobe. Needle aspiration from the nodule yielded evidence of Hashimoto's thyroiditis. The patient also tested strongly positive for antithyroid peroxidase antibodies. Simultaneous laboratory evaluation revealed primary adrenal failure and probable pernicious anaemia, thus producing a diagnosis of Schmidt's syndrome. The patient was initiated on appropriate medical therapy for endocrinopathy. Graves' disease was treated with radioablation.

Original languageEnglish
JournalBMJ Case Reports
DOIs
Publication statusPublished - 21-05-2014

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Autoimmune Polyendocrinopathies
Hashimoto Disease
Graves Disease
Thyroid Function Tests
Sodium Pertechnetate Tc 99m
Pernicious Anemia
Thyrotoxicosis
Hyperthyroidism
Radionuclide Imaging
Peroxidase
Physical Examination
Needles
Fatigue
Weight Loss
Thyroid Gland
Antibodies
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Dasari, Sowjanya ; Naha, Kushal ; Hande, Manjunath ; Vivek, Ganapathiraman. / Hot and cold : Coexistent Graves' disease and Hashimoto's thyroiditis in a patient with Schmidt's syndrome. In: BMJ Case Reports. 2014.
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Hot and cold : Coexistent Graves' disease and Hashimoto's thyroiditis in a patient with Schmidt's syndrome. / Dasari, Sowjanya; Naha, Kushal; Hande, Manjunath; Vivek, Ganapathiraman.

In: BMJ Case Reports, 21.05.2014.

Research output: Contribution to journalArticle

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