The current work emphasizes the modelling of the electroosmosis-modulated peristaltic flow of Jeffery liquid. Such flows emerge in understanding the movement of biological fluids in a microchannel, such as in targeted drug delivery and blood flow through micro arteries. The non-Newtonian fluid flows inside a non-uniform cross-section and an inclined microchannel. The effects of wall properties and variable fluid properties are considered. The long wavelength and small Re number approximations are assumed to simplify the governing equations. Debye-Hückel lineariza-tion is also utilized. The nonlinear governing equations are solved by utilizing the perturbation technique. MATLAB is used for the solution, velocity, temperature, skin friction, coefficient heat transport, concentration, shear wood number, and streamlines expressions. The obtained result in optimal electroosmotic velocity (or Helmholtz-Smoluchowski velocity) increases from −1 to 6; the axial circulation has substantial momentum. For larger optimal electroosmotic velocity, a subsequent boost in an axial electric field causes a significant deceleration. Further, the study helps bio-medical engineers to create biomicrofluidics devices that may aid in carrying biological fluids.
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