Implantable methotrexate films using Poly (E caprolactone) as biodegradable carrier

U. V. Singh, N. Udupa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Biodegradable films of Methotrexate using Poly (E caprolactone) were prepared. The in vitro release was enhanced on incorporation of Poly (glycolic acid). The in vivo degradation of the polymer was faster compared to the in vivo drug release. The histopathological studies showed no deleterious effects at the site of implantation.

Original languageEnglish
Pages (from-to)55-60
Number of pages6
JournalIndian Journal of Pharmaceutical Sciences
Volume59
Issue number2
Publication statusPublished - 03-1997

Fingerprint

glycolic acid
Methotrexate
Polymers
In Vitro Techniques
Drug Liberation
polycaprolactone

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

@article{672094bf8f214a0ca243e5619d03b899,
title = "Implantable methotrexate films using Poly (E caprolactone) as biodegradable carrier",
abstract = "Biodegradable films of Methotrexate using Poly (E caprolactone) were prepared. The in vitro release was enhanced on incorporation of Poly (glycolic acid). The in vivo degradation of the polymer was faster compared to the in vivo drug release. The histopathological studies showed no deleterious effects at the site of implantation.",
author = "Singh, {U. V.} and N. Udupa",
year = "1997",
month = "3",
language = "English",
volume = "59",
pages = "55--60",
journal = "Indian Journal of Pharmaceutical Sciences",
issn = "0250-474X",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "2",

}

Implantable methotrexate films using Poly (E caprolactone) as biodegradable carrier. / Singh, U. V.; Udupa, N.

In: Indian Journal of Pharmaceutical Sciences, Vol. 59, No. 2, 03.1997, p. 55-60.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Implantable methotrexate films using Poly (E caprolactone) as biodegradable carrier

AU - Singh, U. V.

AU - Udupa, N.

PY - 1997/3

Y1 - 1997/3

N2 - Biodegradable films of Methotrexate using Poly (E caprolactone) were prepared. The in vitro release was enhanced on incorporation of Poly (glycolic acid). The in vivo degradation of the polymer was faster compared to the in vivo drug release. The histopathological studies showed no deleterious effects at the site of implantation.

AB - Biodegradable films of Methotrexate using Poly (E caprolactone) were prepared. The in vitro release was enhanced on incorporation of Poly (glycolic acid). The in vivo degradation of the polymer was faster compared to the in vivo drug release. The histopathological studies showed no deleterious effects at the site of implantation.

UR - http://www.scopus.com/inward/record.url?scp=0030916594&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030916594&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0030916594

VL - 59

SP - 55

EP - 60

JO - Indian Journal of Pharmaceutical Sciences

JF - Indian Journal of Pharmaceutical Sciences

SN - 0250-474X

IS - 2

ER -