Implantable methotrexate films using Poly (E caprolactone) as biodegradable carrier

U. V. Singh, N. Udupa

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2 Citations (Scopus)

Abstract

Biodegradable films of Methotrexate using Poly (E caprolactone) were prepared. The in vitro release was enhanced on incorporation of Poly (glycolic acid). The in vivo degradation of the polymer was faster compared to the in vivo drug release. The histopathological studies showed no deleterious effects at the site of implantation.

Original languageEnglish
Pages (from-to)55-60
Number of pages6
JournalIndian Journal of Pharmaceutical Sciences
Volume59
Issue number2
Publication statusPublished - 03-1997

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All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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