Abstract

Background: With the wide usage of highly active antiretroviral therapy, the morbidity and mortality due to HIV have declined gradually. The aim of our study was to determine the cause of mortality among HIV-infected patients and the factors causing early death. Methods: Using medical records of 73 inpatients who are dead, data were collected and analyzed using SPSS version 19 (IBM SPSS Statistics). Chi-square test was performed to determine the factors contributing to early death. A P value <.05 was considered significant. Results: Among 73 deaths, 50 (68.5%) were AIDS related and 23 (31.5%) were non-AIDS related. The most common opportunistic infection causing death was Pneumocystis carinii pneumonia. Early deaths were strongly attributed to low CD4 counts at admission (<100 cells), antiretroviral therapy-naive status, late presentation, and fewer admissions (P value <.05). Conclusion: Although AIDS-defining illness remains the main cause of death in HIV, there is significant number of deaths due to non-HIV-related causes.

Original languageEnglish
Pages (from-to)494-498
Number of pages5
JournalJournal of the International Association of Providers of AIDS Care
Volume16
Issue number5
DOIs
Publication statusPublished - 01-09-2017

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India
Retrospective Studies
Mortality
HIV
Acquired Immunodeficiency Syndrome
Pneumocystis Pneumonia
Opportunistic Infections
Highly Active Antiretroviral Therapy
Chi-Square Distribution
CD4 Lymphocyte Count
Cell- and Tissue-Based Therapy
Medical Records
Inpatients
Cause of Death
Morbidity

All Science Journal Classification (ASJC) codes

  • Immunology
  • Dermatology
  • Infectious Diseases

Cite this

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title = "In-Patient Mortality among PLHIV: A 7-Year Hospital-Based Retrospective Study in Coastal South India",
abstract = "Background: With the wide usage of highly active antiretroviral therapy, the morbidity and mortality due to HIV have declined gradually. The aim of our study was to determine the cause of mortality among HIV-infected patients and the factors causing early death. Methods: Using medical records of 73 inpatients who are dead, data were collected and analyzed using SPSS version 19 (IBM SPSS Statistics). Chi-square test was performed to determine the factors contributing to early death. A P value <.05 was considered significant. Results: Among 73 deaths, 50 (68.5{\%}) were AIDS related and 23 (31.5{\%}) were non-AIDS related. The most common opportunistic infection causing death was Pneumocystis carinii pneumonia. Early deaths were strongly attributed to low CD4 counts at admission (<100 cells), antiretroviral therapy-naive status, late presentation, and fewer admissions (P value <.05). Conclusion: Although AIDS-defining illness remains the main cause of death in HIV, there is significant number of deaths due to non-HIV-related causes.",
author = "Omer Farhan and Basavaprabhu Achappa and Unnikrishnan Bhaskaran and Ramesh Holla and Ramapuram, {John T.} and Satish Rao and Madi, {Deepak R.}",
year = "2017",
month = "9",
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doi = "10.1177/2325957417710721",
language = "English",
volume = "16",
pages = "494--498",
journal = "Journal of the International Association of Providers of AIDS Care",
issn = "2325-9574",
publisher = "SAGE Publications Inc.",
number = "5",

}

TY - JOUR

T1 - In-Patient Mortality among PLHIV

T2 - A 7-Year Hospital-Based Retrospective Study in Coastal South India

AU - Farhan, Omer

AU - Achappa, Basavaprabhu

AU - Bhaskaran, Unnikrishnan

AU - Holla, Ramesh

AU - Ramapuram, John T.

AU - Rao, Satish

AU - Madi, Deepak R.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Background: With the wide usage of highly active antiretroviral therapy, the morbidity and mortality due to HIV have declined gradually. The aim of our study was to determine the cause of mortality among HIV-infected patients and the factors causing early death. Methods: Using medical records of 73 inpatients who are dead, data were collected and analyzed using SPSS version 19 (IBM SPSS Statistics). Chi-square test was performed to determine the factors contributing to early death. A P value <.05 was considered significant. Results: Among 73 deaths, 50 (68.5%) were AIDS related and 23 (31.5%) were non-AIDS related. The most common opportunistic infection causing death was Pneumocystis carinii pneumonia. Early deaths were strongly attributed to low CD4 counts at admission (<100 cells), antiretroviral therapy-naive status, late presentation, and fewer admissions (P value <.05). Conclusion: Although AIDS-defining illness remains the main cause of death in HIV, there is significant number of deaths due to non-HIV-related causes.

AB - Background: With the wide usage of highly active antiretroviral therapy, the morbidity and mortality due to HIV have declined gradually. The aim of our study was to determine the cause of mortality among HIV-infected patients and the factors causing early death. Methods: Using medical records of 73 inpatients who are dead, data were collected and analyzed using SPSS version 19 (IBM SPSS Statistics). Chi-square test was performed to determine the factors contributing to early death. A P value <.05 was considered significant. Results: Among 73 deaths, 50 (68.5%) were AIDS related and 23 (31.5%) were non-AIDS related. The most common opportunistic infection causing death was Pneumocystis carinii pneumonia. Early deaths were strongly attributed to low CD4 counts at admission (<100 cells), antiretroviral therapy-naive status, late presentation, and fewer admissions (P value <.05). Conclusion: Although AIDS-defining illness remains the main cause of death in HIV, there is significant number of deaths due to non-HIV-related causes.

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DO - 10.1177/2325957417710721

M3 - Article

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JF - Journal of the International Association of Providers of AIDS Care

SN - 2325-9574

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