The free radical scavenging potential of the leaves of A. squamosa was studied by using different antioxidant models of screening. The ethanolic extract at 1000 μg/ ml showed maximum scavenging of the radical cation, 2,2- azinobis- (3-ethylbenzothiazoline- 6- sulphonate) (ABTS) observed upto 99.07% followed by the scavenging of the stable radical 1,1-diphenyl, 2- picryl hydrazyl (DPPH) (89.77%) and nitric oxide radical (73.64%) at the same concentration. However, the extract showed only moderate scavenging activity of superoxide radicals and antilipid peroxidation potential, which was performed using rat- brain homogenate. The findings justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
|Number of pages||5|
|Journal||Indian Journal of Experimental Biology|
|Publication status||Published - 2004|
Shirwaikar, A., Rajendran, K., & Kumar, C. D. (2004). In vitro antioxidant studies of Annona squamosa Linn. Leaves. Indian Journal of Experimental Biology, 42(8), 803-807. https://www.scopus.com/inward/record.uri?eid=2-s2.0-4043114243&partnerID=40&md5=cca39b6e021c86747de26ae67e500b72