In vitro antioxidant studies of Sphaeranthus indicus (Linn)

A. Shirwaikar, K.S. Prabhu, I.S.R. Punitha

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

The free radical scavenging potential of the plant S.indicus was studied by using different antioxidant models of screening. The ethanolic extract at 1000 μg/ml showed maximum scavenging of the radical cation, 2,2-azinobis-(3- ethylbenzothiazoline-6-sulphonate) (ABTS) observed upto 41.99 % followed by the scavenging of the stable radical 1,1-diphenyl, 2-picryl hydrazyl (DPPH) (33.27 %), superoxide dismutase (25.14 %) and nitric oxide radical (22.36 %) at the same concentration. However, the extract showed only moderate scavenging activity of iron chelation (14.2 %). Total antioxidant capacity of the extract was found to be 160.85 nmol/g ascorbic acid. The results justify the therapeutic applications of the plant in the indigenous system of medicine, augmenting its therapeutic value.
Original languageEnglish
Pages (from-to)993-996
Number of pages4
JournalIndian Journal of Experimental Biology
Volume44
Issue number12
Publication statusPublished - 2006
Externally publishedYes

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