In vitro studies on peroxidative changes leading to hemolysis of erythrocytes infested with malarial parasite Plasmodium vivax

S. Meera, Ashalatha V. Rao, Vivian D'Souza, Shrinivas B. Rao

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3 Citations (Scopus)

Abstract

Blood erythrocytes of 25 confirmed malarial patients infested with P. vivax were analyzed for peroxidation and hemolysis and results compared with 10 uninfected normal control samples. Results indicated significant increase in peroxide formation measured as malondialdehyde, both in presence and absence of H2O2, in parasite infested erythrocytes. These changes induced hemolysis of infected erythrocytes which was increased manifold in presence of H2O2 and could probably be the reason for extensive anemia reported in malaria.

Original languageEnglish
Pages (from-to)729-730
Number of pages2
JournalIndian Journal of Experimental Biology
Volume37
Issue number7
Publication statusPublished - 01-07-1999
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Bioengineering

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