Influence of egg albumin of dissolution of methotrexate

U. V. Singh, N. Udupa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Solid dispersion of methotrexate (MTX) was prepared using natural polymer egg albumin. The in vitro release of MTX was faster from solid dispersions. The interaction in solid state as revealed by XRD and DSC showed that the crystallinity of the drug was affected. It is predicted that there may be complex formation between the two components.

Original languageEnglish
Pages (from-to)333-335
Number of pages3
JournalIndian Journal of Pharmaceutical Sciences
Volume59
Issue number6
Publication statusPublished - 11-1997

Fingerprint

Methotrexate
Ovum
Albumins
Polymers
Pharmaceutical Preparations
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

@article{1ec0496f17b34bcf9d704c0da4f2fadd,
title = "Influence of egg albumin of dissolution of methotrexate",
abstract = "Solid dispersion of methotrexate (MTX) was prepared using natural polymer egg albumin. The in vitro release of MTX was faster from solid dispersions. The interaction in solid state as revealed by XRD and DSC showed that the crystallinity of the drug was affected. It is predicted that there may be complex formation between the two components.",
author = "Singh, {U. V.} and N. Udupa",
year = "1997",
month = "11",
language = "English",
volume = "59",
pages = "333--335",
journal = "Indian Journal of Pharmaceutical Sciences",
issn = "0250-474X",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "6",

}

Influence of egg albumin of dissolution of methotrexate. / Singh, U. V.; Udupa, N.

In: Indian Journal of Pharmaceutical Sciences, Vol. 59, No. 6, 11.1997, p. 333-335.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Influence of egg albumin of dissolution of methotrexate

AU - Singh, U. V.

AU - Udupa, N.

PY - 1997/11

Y1 - 1997/11

N2 - Solid dispersion of methotrexate (MTX) was prepared using natural polymer egg albumin. The in vitro release of MTX was faster from solid dispersions. The interaction in solid state as revealed by XRD and DSC showed that the crystallinity of the drug was affected. It is predicted that there may be complex formation between the two components.

AB - Solid dispersion of methotrexate (MTX) was prepared using natural polymer egg albumin. The in vitro release of MTX was faster from solid dispersions. The interaction in solid state as revealed by XRD and DSC showed that the crystallinity of the drug was affected. It is predicted that there may be complex formation between the two components.

UR - http://www.scopus.com/inward/record.url?scp=0031440994&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031440994&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0031440994

VL - 59

SP - 333

EP - 335

JO - Indian Journal of Pharmaceutical Sciences

JF - Indian Journal of Pharmaceutical Sciences

SN - 0250-474X

IS - 6

ER -